Luteoma

Last update 08 May 2025

Basic Info

Synonyms

Gestational Luteoma, Gestational Luteomas, Luteal Cell Neoplasm

+ [31]

Introduction

An ovarian neoplasm composed of LUTEAL CELLS derived from luteinized GRANULOSA CELLS and THECA CELLS. Luteomas respond to GONADOTROPINS, and vary in their hormone production (PROGESTERONE; ESTROGENS; or ANDROGENS). During PREGNANCY, a transient type of luteoma may develop due to an exaggerated LUTEINIZATION of the OVARY.

100 Clinical Results associated with Luteoma

100 Translational Medicine associated with Luteoma

0 Patents (Medical) associated with Luteoma

309

Literatures (Medical) associated with Luteoma

01 Jan 2025·Veterinary Radiology & Ultrasound

Computed tomographic findings in dogs with ovarian tumors: A tortuous ovarian artery consistently identifies ovarian origin in complex abdominal masses

Article

Author: Panopoulos, Ioannis ; Lopez, Cristobal ; Schwarz, Tobias ; Massarenti, Chiara ; Baldinetti, Manuela ; Fournier, Quentin ; Morabito, Simona ; Manfredi, Martina ; Thierry, Florence ; Zani, Davide Danilo ; Longo, Maurizio

AbstractThe aim of this retrospective multicentric case series is to describe the CT findings of ovarian neoplasia in dogs. Twenty dogs with pre‐ and postcontrast CT exams and cytological/histological diagnosis of ovarian neoplasia were included. Five dogs presented with bilateral tumors, for a total of 25 neoplasms: 15 carcinomas (4 bilateral), 4 granulosa cell tumors, 2 poorly differentiated malignant neoplasia (bilateral), 2 luteomas, 1 teratoma, 1 dysgerminoma. In two dogs, the tumor developed from an ovarian remnant. Ovarian tumors showed variable size, lobulated shape, and precontrast heterogenous appearance. Mineral foci and/or fat components were rare, observed in teratoma, granulosa cell tumors (2), and ovarian carcinoma. Tumor type was not found to be associated with any CT features. Larger masses were more likely located in the central abdomen ventral to the ipsilateral kidney, demonstrated signs of tumor rupture, and were associated with abdominal or sternal lymphadenopathy and peritoneal effusion. A tortuous ovarian artery was constantly detectable, associated with an enlarged gonadal vein (12 cases). Related cavitary changes were peritoneal effusion (14 dogs) and sternal lymphadenopathy (7 dogs). Presumed or confirmed metastasis was reported in 9 of 20 cases, with CT evidence of transcoelomic (serosal thickening, peritoneal nodules, omental cake, implant lesions to the liver, spleen, and diaphragm), lymphatic and hematogenous spread (lungs, liver, bone, muscles, and spleen). In conclusion, the present study reports the CT features of different canine ovarian neoplasia. A tortuous ovarian artery may be useful to consistently recognize the ovarian origin of a large abdominal mass.

07 Sep 2024·Cureus

Bilateral Pregnancy Luteoma Presenting as Acute Abdomen in a Young Female: A Case Report

Article

Author: Hasan, Abdul Haseeb ; Nadeem, Muhammad F ; Nawaz, Rabia ; Ahmed, Zeeshan ; Abid, Muhammad Ali ; Nauman, Hooriea

Pregnancy luteoma (PL) is a rare, non-neoplastic ovarian lesion that can mimic malignant ovarian tumors, posing significant diagnostic challenges. PL typically presents as asymptomatic, unilateral, or bilateral ovarian masses and is often discovered incidentally. Its development is linked to hormonal fluctuations during pregnancy, particularly elevated human chorionic gonadotropin (hCG) levels. While PL generally resolves postpartum, complications such as torsion may necessitate surgical intervention. We report the case of a 23-year-old primigravida presenting with acute abdominal pain, vomiting, and abdominal distention at 13 weeks gestation. Imaging revealed large, bilateral multicystic ovarian masses. Elevated CA-125 levels raised suspicion for malignancy, leading to a laparotomy and bilateral oophorectomy. Histopathological analysis confirmed the diagnosis of pregnancy luteoma.

01 Sep 2024·BMJ Case Reports

Ovarian luteoma masses in pregnancy: an uncommon cause of virilisation

Article

Author: Twidale, Emily ; Stewart, Isabella

Pregnancy luteoma is a benign ovarian tumour that presents during pregnancy and regresses spontaneously post partum. The mass may secrete androgenic hormones which can result in virilisation of mother and female foetus. Clinical presentation of pregnancy luteoma is varied from asymptomatic to significant virilisation. We present two cases of ovarian luteomas identified incidentally at caesarean section. The first case had marked hirsutism, while the second case had mild acne. Both foetuses were male and appeared unaffected at birth. Where maternal virilisation is identified during pregnancy, differential diagnoses including pregnancy luteoma should be considered.

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