Last update 08 May 2025

Hypophosphatasia, Perinatal Lethal

Basic Info

Synonyms
HPPN, HYPOPHOSPHATASIA, PERINATAL LETHAL, Hypophosphatasia, Perinatal Lethal
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Introduction
A rare, genetic form of hypophosphatasia (HPP) characterized by markedly impaired bone mineralization <i>in utero</i> due to reduced activity of serum alkaline phosphatase (ALP) and causing stillbirth or respiratory failure within days of birth.

Analysis

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