Umbilical cord Mesenchymal stem cell( Institute of Liver & Biliary Sciences)

Liver disease deaths are rising, but transplants remain scarce in India. With over 100,000 needed annually and only
2,500 performed, non-transplant options are urgently needed. Regenerative therapy, especially MSCs, shows promise but lacks validation, particularly for non-viral ACLF. The proposed NC-CHRM aims to develop and validate MSC-based therapy to promote native liver regeneration and offer a safe, effective, transplant-free treatment.

Liver disease deaths are rising, but transplants remain scarce in India. With over 100,000 needed annually and only
2,500 performed, non-transplant options are urgently needed. Regenerative therapy, especially MSCs, shows promise but lacks validation, particularly for non-viral Acute on Chronic Liver Failure (ACLF). The proposed NC-CHRM aims to develop and validate MSC-based therapy to promote native liver regeneration and offer a safe, effective, transplant-free treatment.