Last update 08 May 2025

Vicriviroc/MK-2048

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
MK 2048/vicriviroc, Vicriviroc/MK 2048
+ [7]
Target
CCR5 x HIV integrase
Action
antagonists, inhibitors
Mechanism
CCR5 antagonists(C-C chemokine receptor type 5 antagonists), HIV-1 integrase inhibitors(HIV integrase inhibitors), Virus internalization inhibitors
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
HIV Infections
Originator Organization
National Institute of Allergy & Infectious Diseases
Active Organization-
Inactive Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.National Institute of Allergy & Infectious Diseases
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC28H38F3N5O2
InChIKeyCNPVJJQCETWNEU-CYFREDJKSA-N
CAS Registry306296-47-9
View All Structures (2)

Related

2
Clinical Trials associated with Vicriviroc/MK-2048
NCT02419456
/ CompletedPhase 1IIT
Phase 1 Pharmacokinetic Trial of Two Intravaginal Rings (IVRs) Containing Different Dose Strengths of Vicriviroc (MK-4176) and MK-2048
NCT02356302
/ CompletedPhase 1IIT
Phase 1 Safety and Pharmacokinetics Study of MK-2048/Vicriviroc (MK-4176)/MK-2048A Intravaginal Rings
100 Clinical Results associated with Vicriviroc/MK-2048
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100 Translational Medicine associated with Vicriviroc/MK-2048
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100 Patents (Medical) associated with Vicriviroc/MK-2048
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100 Deals associated with Vicriviroc/MK-2048
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 1-
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Approval

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Regulation

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