Last update 30 May 2026

GSK-586529

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
586529, GSK 586529, GSK586529
Target
CRHR1
Action
antagonists
Mechanism
CRHR1 antagonists(Corticotropin-releasing factor receptor 1 antagonists)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication-
Inactive Indication
Anxiety DisordersDepressive Disorder
Originator Organization
GSK PlcGSK Plc
Active Organization-
Inactive Organization
GSK PlcGSK Plc
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with GSK-586529
NCT00703547
/ CompletedPhase 1
A Single Blind, Randomized, Placebo Controlled, Crossover Study to Investigate the Safety, Tolerability and Pharmacokinetics of Single Oral Escalating Doses of GSK586529 in Healthy Volunteers
100 Clinical Results associated with GSK-586529
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100 Translational Medicine associated with GSK-586529
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100 Patents (Medical) associated with GSK-586529
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100 Deals associated with GSK-586529
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anxiety DisordersPhase 1
United Kingdom
GSK PlcGSK Plc
28 Jan 2008
Depressive DisorderPhase 1
United Kingdom
GSK PlcGSK Plc
28 Jan 2008
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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