Last update 08 Aug 2026

89Zr-Trastuzumab-DM1

Overview

Basic Info

Drug Type
Dual payload Antibody drug conjugate (Dual payload ADC), Diagnostic radiopharmaceuticals
Synonyms
89 Zr-labeled T-DM1
Target
HER2 x Tubulin
Action
antagonists, inhibitors
Mechanism
HER2 antagonists(Receptor tyrosine-protein kinase erbB-2 antagonists), Tubulin inhibitors
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication-
Inactive Indication
HER2 Positive Breast Cancer
Originator Organization
University of TorontoUniversity of Toronto
Active Organization-
Inactive Organization
University of TorontoUniversity of Toronto
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC35H48ClN3O10S
InChIKeyANZJBCHSOXCCRQ-FKUXLPTCSA-N
CAS Registry139504-50-0
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Related

100 Clinical Results associated with 89Zr-Trastuzumab-DM1
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100 Translational Medicine associated with 89Zr-Trastuzumab-DM1
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100 Patents (Medical) associated with 89Zr-Trastuzumab-DM1
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100 Deals associated with 89Zr-Trastuzumab-DM1
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HER2 Positive Breast CancerPreclinical
Canada
University of TorontoUniversity of Toronto
21 Sep 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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