Last update 06 Dec 2025

DTPA[In-111]-dinutuximab-IRDye800CW

Overview

Basic Info

Drug Type
Radiolabeled antibody, Diagnostic radiopharmaceuticals
Synonyms
[In-111]DTPA-dinutuximab-IRDye800CW, DTPA[Indium-111]-dinutuximab-IRDye800CW
Target
GD2
Action
inhibitors
Mechanism
GD2 inhibitors(Disialoganglioside GD2 inhibitors), ADCC(Antibody-dependent cell-mediated cytotoxicity (ADCC) effects), Complement dependent cytotoxicity (CDC) effects
Therapeutic Areas
NeoplasmsOther Diseases
Active Indication
Neuroblastoma
Inactive Indication-
Originator Organization
University of PittsburghUniversity of Pittsburgh
Active Organization
University of PittsburghUniversity of Pittsburgh
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
RegulationOrphan Drug (United States)

Structure/Sequence

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Related

100 Clinical Results associated with DTPA[In-111]-dinutuximab-IRDye800CW
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100 Translational Medicine associated with DTPA[In-111]-dinutuximab-IRDye800CW
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100 Patents (Medical) associated with DTPA[In-111]-dinutuximab-IRDye800CW
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100 Deals associated with DTPA[In-111]-dinutuximab-IRDye800CW
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeuroblastomaDiscovery
United States
University of PittsburghUniversity of Pittsburgh
31 Jul 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.
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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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