Last update 11 Apr 2026

TREM2 stimulants(Smith, Gambrell & Russell)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound 18(Smith, Gambrell & Russell)
Target
TREM2
Action
stimulants
Mechanism
TREM2 stimulants(Triggering receptor expressed on myeloid cells 2 stimulants)
Therapeutic Areas
Nervous System DiseasesEndocrinology and Metabolic Disease
Active Indication
Parkinson Disease
Inactive Indication-
Originator Organization
Smith, Gambrell & Russell LLPSmith, Gambrell & Russell LLP
Active Organization
Smith, Gambrell & Russell LLPSmith, Gambrell & Russell LLP
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC25H22ClF4N7O2
InChIKeyRQFJXGHMXMTHRL-SGTLLEGYSA-N
CAS Registry3064830-77-6

Related

100 Clinical Results associated with TREM2 stimulants(Smith, Gambrell & Russell)
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100 Translational Medicine associated with TREM2 stimulants(Smith, Gambrell & Russell)
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100 Patents (Medical) associated with TREM2 stimulants(Smith, Gambrell & Russell)
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1
Literatures (Medical) associated with TREM2 stimulants(Smith, Gambrell & Russell)
08 May 2025ACS Medicinal Chemistry Letters
Novel Pyrido[3,4-d]pyrimidin-4-one and Pyrimido[5,4-d]pyrimidin-4-one Derivatives as TREM2 Agonists for Treating Parkinson’s Disease
100 Deals associated with TREM2 stimulants(Smith, Gambrell & Russell)
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Parkinson DiseaseDiscovery
United Kingdom
Smith, Gambrell & Russell LLPSmith, Gambrell & Russell LLP
02 Apr 2025
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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