Last update 13 Dec 2025

mGluR2 negative allosteric modulator(Emory University)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Compound 7(Emory University)
Target
mGluR2
Action
negative allosteric modulator
Mechanism
mGluR2 negative allosteric modulator(Metabotropic glutamate receptor 2 negative allosteric modulator)
Therapeutic Areas
Nervous System DiseasesOther Diseases
Active Indication
Alzheimer DiseaseAnxiety DisordersDepressive Disorder+ [1]
Inactive Indication-
Originator Organization
Emory UniversityEmory University
Active Organization
Emory UniversityEmory University
Inactive Organization-
License Organization-
Drug Highest PhaseDiscovery
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC18H13F2N3O
InChIKeyUYPRIXVJTXCLQJ-UHFFFAOYSA-N
CAS Registry3055536-68-7

Related

100 Clinical Results associated with mGluR2 negative allosteric modulator(Emory University)
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100 Translational Medicine associated with mGluR2 negative allosteric modulator(Emory University)
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100 Patents (Medical) associated with mGluR2 negative allosteric modulator(Emory University)
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1
Literatures (Medical) associated with mGluR2 negative allosteric modulator(Emory University)
10 Apr 2025ACS Medicinal Chemistry Letters
Novel 6-Aryl isoindolin-1-one Derivatives as Negative Allosteric Modulators of Metabotropic Glutamate Receptor 2
100 Deals associated with mGluR2 negative allosteric modulator(Emory University)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseaseDiscovery
United States
Emory UniversityEmory University
19 Mar 2025
Anxiety DisordersDiscovery
United States
Emory UniversityEmory University
19 Mar 2025
Depressive DisorderDiscovery
United States
Emory UniversityEmory University
19 Mar 2025
SchizophreniaDiscovery
United States
Emory UniversityEmory University
19 Mar 2025
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Clinical Result

Indication
Phase
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Study
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Clinical Trial

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Approval

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Regulation

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