Last update 29 Aug 2025

Anti-EphA2 receptor antibody-5'ppp-siPLK1 conjugates(University of Strasbourg)

Overview

Basic Info

Drug Type
Antibody–siRNA conjugates (ARC)
Synonyms-
Target
EphA2 x PLK1 x RIG-I
Action
antagonists, inhibitors, stimulants
Mechanism
EphA2 antagonists(Ephrin type-A receptor 2 antagonists), PLK1 inhibitors(Polo like kinase 1 inhibitors), RIG-I stimulants(Retinoic acid-inducible gene I stimulants)
Therapeutic Areas
Neoplasms
Active Indication-
Inactive Indication
Neoplasms
Originator Organization
University of StrasbourgUniversity of StrasbourgSanofiSanofi
Active Organization-
Inactive Organization
University of StrasbourgUniversity of StrasbourgSanofiSanofi
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

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Related

100 Clinical Results associated with Anti-EphA2 receptor antibody-5'ppp-siPLK1 conjugates(University of Strasbourg)
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100 Translational Medicine associated with Anti-EphA2 receptor antibody-5'ppp-siPLK1 conjugates(University of Strasbourg)
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100 Patents (Medical) associated with Anti-EphA2 receptor antibody-5'ppp-siPLK1 conjugates(University of Strasbourg)
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100 Deals associated with Anti-EphA2 receptor antibody-5'ppp-siPLK1 conjugates(University of Strasbourg)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
NeoplasmsPreclinical
France
University of StrasbourgUniversity of Strasbourg
01 Jul 2021
NeoplasmsPreclinical
France
SanofiSanofi
01 Jul 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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