Last update 06 Jun 2026

AUT06NG

Overview

Basic Info

Drug Type
CAR-T
Synonyms
ATIMP
Target
GD2
Action
inhibitors
Mechanism
GD2 inhibitors(Disialoganglioside GD2 inhibitors)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
Refractory NeuroblastomaDiffuse midline glioma, point mutation K27M in histone H3
Inactive Indication
OsteosarcomaSkin NeoplasmsSmall Cell Lung Cancer
Originator Organization
University College LondonUniversity College London
Active Organization
University College LondonUniversity College London
Inactive Organization
Autolus Ltd.
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with AUT06NG
NCT05990751
/ Active, not recruitingPhase 1IIT
Multi-modular Chimeric Antigen Receptor Targeting GD2 in Neuroblastoma
NCT05544526
/ RecruitingPhase 1IIT
Chimeric Antigen Receptor (CAR)-T Cells to Target GD2 for Diffuse Midline Glioma
100 Clinical Results associated with AUT06NG
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100 Translational Medicine associated with AUT06NG
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100 Patents (Medical) associated with AUT06NG
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100 Deals associated with AUT06NG
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory NeuroblastomaPhase 1
United Kingdom
University College LondonUniversity College London
19 Apr 2024
Diffuse midline glioma, point mutation K27M in histone H3Phase 1
United Kingdom
University College LondonUniversity College London
15 Aug 2023
NeuroblastomaPreclinical-
Autolus Ltd.
-
OsteosarcomaPreclinical-
Autolus Ltd.
-
Skin NeoplasmsPreclinical-
Autolus Ltd.
-
Small Cell Lung CancerPreclinical-
Autolus Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Core Patent

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Clinical Trial

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Approval

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Regulation

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