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Last update 03 Jun 2026
GenSci145
Last update 03 Jun 2026
Overview
Basic Info
Drug Type Small molecule drug |
Synonyms- |
Target |
Action inhibitors |
Mechanism PI3Kα inhibitors(Phosphatidylinositol 3 kinase alpha inhibitors) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePhase 1/2 |
First Approval Date- |
Regulation- |
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Related
1
Clinical Trials associated with GenSci145NCT07407504
An International, Multicenter, Open-label, Phase 1/2 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics, and Efficacy of GenSci145, as Monotherapy or in Combination Therapy, in Participants With PIK3CA-mutated, Locally Advanced or Metastatic Solid Tumors.
100 Clinical Results associated with GenSci145
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100 Translational Medicine associated with GenSci145
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100 Patents (Medical) associated with GenSci145
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100 Deals associated with GenSci145
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| PIK3CA positive Solid Tumors | Phase 2 | China | 11 Mar 2026 | |
| Advanced breast cancer | Phase 1 | China | 01 Apr 2026 | |
| Brain metastases | Phase 1 | China | 01 Apr 2026 | |
| Colorectal Cancer | Phase 1 | China | 01 Apr 2026 | |
| Female Genital Neoplasms | Phase 1 | China | 01 Apr 2026 | |
| Hormone receptor positive HER2 negative breast cancer | Phase 1 | China | 01 Apr 2026 | |
| Locally Advanced Malignant Solid Neoplasm | Phase 1 | China | 01 Apr 2026 | |
| PIK3CA H1047R mutant Solid Tumors | Phase 1 | China | 01 Apr 2026 | |
| Squamous Cell Carcinoma of Head and Neck | Phase 1 | China | 01 Apr 2026 | |
| Non-Small Cell Lung Cancer | Preclinical | China | 01 Aug 2025 |
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