Last update 08 May 2025

MK-8558

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target-
Action-
Mechanism-
Therapeutic Areas
Immune System DiseasesInfectious DiseasesUrogenital Diseases
Active Indication-
Inactive Indication
HIV Infections
Originator Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
Active Organization-
Inactive Organization
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
License Organization-
Drug Highest PhasePendingPhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with MK-8558
NCT03859739
/ CompletedPhase 1
A Single-Dose Clinical Trial to Study the Safety, Tolerability, Pharmacokinetics, and Anti-Retroviral Activity of MK-8558 Monotherapy in Anti-Retroviral-Naïve HIV-1 Infected Participants
100 Clinical Results associated with MK-8558
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100 Translational Medicine associated with MK-8558
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100 Patents (Medical) associated with MK-8558
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100 Deals associated with MK-8558
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
HIV InfectionsPhase 1
Romania
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
26 Apr 2019
HIV InfectionsPhase 1
Germany
Merck Sharp & Dohme Corp.Merck Sharp & Dohme Corp.
26 Apr 2019
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date
NCT03859739 (8558-002 | MK-8558-002, CTgov)
Phase 1
HIV Infections
21
(MK-8558 400 mg)
lshhimnvty(xkokbojgah) = qlgbzscmon lfogtgyres (ayoemrdctr, qrdteeaifw - hhrllfpchb)
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-
28 May 2021
(MK-8558 900 mg)
lshhimnvty(xkokbojgah) = zynwjajhof lfogtgyres (ayoemrdctr, gulviwcwqp - htifvuqknt)
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Translational Medicine

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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