Last update 13 Jun 2025

Fluticasone Furoate/Umeclidinium Bromide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Fluticasone furoate/umeclidinium, Umeclidinium/fluticasone furoate, GSK 685698/GSK 573719
+ [1]
Target
GR x M1 receptor x M2 receptor x M3 receptor x M4 receptor x M5 receptor
Action
agonists, antagonists
Mechanism
GR agonists(Glucocorticoid receptor agonists), M1 receptor antagonists(Muscarinic acetylcholine receptor M1 antagonists), M2 receptor antagonists(Muscarinic acetylcholine receptor M2 antagonists)
Therapeutic Areas
Other Diseases
Active Indication-
Inactive Indication
Asthma-Chronic Obstructive Pulmonary Disease Overlap Syndrome
Originator Organization
GSK PlcGSK Plc
Active Organization-
Inactive Organization
GlaxoSmithKline Research & Development Ltd.
License Organization-
Drug Highest PhasePendingPhase 2
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC29H34BrNO2
InChIKeyPEJHHXHHNGORMP-UHFFFAOYSA-M
CAS Registry869113-09-7
View All Structures (2)

Related

1
Clinical Trials associated with Fluticasone Furoate/Umeclidinium Bromide
EUCTR2014-000883-16-DE
/ Not yet recruitingPhase 2
A Clinical Study to Evaluate Four Doses of Umeclidinium Bromide in Combination with Fluticasone Furoate in COPD Subjects with an Asthmatic Component
100 Clinical Results associated with Fluticasone Furoate/Umeclidinium Bromide
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100 Translational Medicine associated with Fluticasone Furoate/Umeclidinium Bromide
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100 Patents (Medical) associated with Fluticasone Furoate/Umeclidinium Bromide
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100 Deals associated with Fluticasone Furoate/Umeclidinium Bromide
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Asthma-Chronic Obstructive Pulmonary Disease Overlap SyndromePhase 2
Germany
GlaxoSmithKline Research & Development Ltd.
-
Asthma-Chronic Obstructive Pulmonary Disease Overlap SyndromePhase 2
Poland
GlaxoSmithKline Research & Development Ltd.
-
Asthma-Chronic Obstructive Pulmonary Disease Overlap SyndromePhase 2
Romania
GlaxoSmithKline Research & Development Ltd.
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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