Delving into the Latest Updates on Codeine Phosphate/Guaifenesin with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms-

Target

Opioid receptors

Action

agonists

Mechanism

Opioid receptors agonists(Opioid receptors agonists)

Therapeutic Areas

Infectious DiseasesRespiratory Diseases

Active Indication

Common ColdCough

Inactive Indication-

Originator Organization-

Active Organization-

Inactive Organization-

License Organization-

Drug Highest PhaseApproved

First Approval Date-

Regulation-

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Structure/Sequence

Molecular FormulaC10H14O4

InChIKeyHSRJKNPTNIJEKV-UHFFFAOYSA-N

CAS Registry93-14-1

View All Structures (2)

The objectives of this pivotal study are:
1. to evaluate bioavailability of an extended-release and immediate release Codeine Phosphate/Guaifenesin tablet at steady state following multiple oral administration
2. to assess the safety and tolerability of this Codeine Phosphate/Guaifenesin extended release formulation.

Start Date01 Oct 2014

Sponsor / Collaborator

Nexgen Pharma (TM), Inc.

[+1]

NCT02157649

/ CompletedPhase 1

An Open-Label, Single-Dose, Crossover Comparative Bioavailability and Pharmacokinetic Study of Codeine Phosphate/Guaifenesin Extended-Release Tablet With Immediate-Release Tablet

The objectives of this study are (a) to determine if drug levels from a single dose of an extended-release Codeine/Guaifenesin tablet are similar to an immediate-release tablet given every four hours containing lower doses considered safe for over-the-counter use; (b) to evaluate if food affects the drug levels of this extended-release Codeine/Guaifenesin tablet after a single administration; and (c) to assess the safety and tolerability of the Codeine/Guaifenesin extended-release and immediate release tablet formulations.

Start Date01 Jun 2014

Sponsor / Collaborator

Nexgen Pharma (TM), Inc.

100 Clinical Results associated with Codeine Phosphate/Guaifenesin

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100 Translational Medicine associated with Codeine Phosphate/Guaifenesin

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100 Patents (Medical) associated with Codeine Phosphate/Guaifenesin

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100 Deals associated with Codeine Phosphate/Guaifenesin

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