Last update 05 Jul 2025

JTCR-016

Overview

Basic Info

Drug Type
TCR-T Cell therapy
Synonyms
High-affinity WT1-specific TCR T cells - Juno Therapeutics, HLA-A2/WT1-specific TCR T cells - Juno TherapeuticsWT1-sensitised T cells - Juno Therapeutics, JTCR 016
+ [1]
Target
WT1
Action
inhibitors
Mechanism
WT1 inhibitors(Wilms' Tumour 1 inhibitors), Immunologic cytotoxicity, T lymphocyte replacements
Therapeutic Areas
NeoplasmsImmune System DiseasesHemic and Lymphatic Diseases+ [1]
Active Indication-
Inactive Indication
Acute Lymphoblastic LeukemiaMesotheliomaMyelodysplastic Syndromes+ [2]
Originator Organization
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
Active Organization-
Inactive Organization
Juno Therapeutics, Inc.Juno Therapeutics, Inc.Fred Hutchinson Cancer Research CenterFred Hutchinson Cancer Research Center
License Organization-
Drug Highest PhasePendingPhase 1/2
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with JTCR-016
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100 Translational Medicine associated with JTCR-016
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100 Patents (Medical) associated with JTCR-016
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100 Deals associated with JTCR-016
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Non-Small Cell Lung CancerPhase 2
United States
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
22 May 2015
MesotheliomaPhase 2
United States
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
24 Apr 2015
Acute Lymphoblastic LeukemiaPhase 2
United States
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
21 Dec 2012
Myelodysplastic SyndromesPhase 2
United States
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
28 Nov 2012
Philadelphia chromosome positive chronic myelogenous leukemiaPhase 2
United States
Juno Therapeutics, Inc.Juno Therapeutics, Inc.
15 Nov 2012
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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