Last update 31 Jan 2026

ISM012-077

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Erythropoietin release stimulator (Insilico Medicine), Prolyl hydroxylase domain 2 (PHD2) inhibitor (Insilico Medicine)
Target
PHD2
Action
inhibitors
Mechanism
PHD2 inhibitors(egl-9 family hypoxia inducible factor 1 inhibitors)
Therapeutic Areas
Hemic and Lymphatic DiseasesUrogenital Diseases
Active Indication
Anemia in chronic kidney disease
Inactive Indication-
Originator Organization
InSilico Medicine, Inc.
Active Organization
InSilico Medicine Hong Kong Ltd.InSilico Medicine Hong Kong Ltd.
Inactive Organization
InSilico Medicine, Inc.
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Related

100 Clinical Results associated with ISM012-077
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100 Translational Medicine associated with ISM012-077
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100 Patents (Medical) associated with ISM012-077
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100 Deals associated with ISM012-077
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia in chronic kidney diseasePreclinical
China
InSilico Medicine Hong Kong Ltd.InSilico Medicine Hong Kong Ltd.
30 Jan 2022
AnemiaPreclinical
Hong Kong
InSilico Medicine, Inc.
06 Jan 2021
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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