Pharmaceutical Insights
Navigate pharmaceutical trends with our insights on targets, institutional pipelines, clinical advances, and new drugs.
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Recent blog posts
SGLT2 Inhibitors - The Cross-Domain Superstar of Antidiabetic Drugs
SGLT2 Inhibitors - The Cross-Domain Superstar of Antidiabetic Drugs
2 September 2023
SGLT2 inhibitors use a unique insulin-independent mechanism to lower blood glucose levels, not only effectively and safely reducing glucose, but also providing significant cardio-renal protection.
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Bristol-Myers Squibb’s mavacamten has announced long-term follow-up data from two phase 3 trials for the treatment of hypertrophic cardiomyopathy
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Bristol-Myers Squibb’s mavacamten has announced long-term follow-up data from two phase 3 trials for the treatment of hypertrophic cardiomyopathy
2 September 2023
Recently, Bristol Myers Squibb has announced the latest long-term follow-up results of two Phase 3 studies that assessed the treatment efficacy of Camzyos (mavacamten).
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Roche's PD-L1 monoclonal antibody, Atezolizumab subcutaneous formulation, has received approval for marketing by the UK's MHRA
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Roche's PD-L1 monoclonal antibody, Atezolizumab subcutaneous formulation, has received approval for marketing by the UK's MHRA
2 September 2023
Recently, Roche announced that its PD-L1 targeted antibody, Tecentriq(atezolizumab), has been approved for marketing in the UK by the Medicines and Healthcare products Regulatory Agency (MHRA).
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The Phase 1 clinical trial for the KRAS G12D inhibitor MRTX1133, developed by Mirati, has been launched
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The Phase 1 clinical trial for the KRAS G12D inhibitor MRTX1133, developed by Mirati, has been launched
2 September 2023
the combined therapy of KRAS G12D inhibitor MRTX1133 and immune checkpoint inhibitors can cause sustained tumor elimination and significantly improve the survival outcomes in mice.
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FibroGen's CTGF antibody Pamrevlumab failed in phase III clinical trials for DMD treatment
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FibroGen's CTGF antibody Pamrevlumab failed in phase III clinical trials for DMD treatment
2 September 2023
On August 29, FibroGen announced that the CTGF antibody Pamrevlumab for the treatment of Duchenne Muscular Dystrophy (DMD) in the phase three LELANTOS clinical trial did not achieve its primary NSAA endpoint and crucial secondary endpoints.
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The Mechanism of Interferons Antiviral Action and Its Biological Activity
Advanced Tech.
5 min read
The Mechanism of Interferons Antiviral Action and Its Biological Activity
2 September 2023
Interferon (IFN) is a type of crucial cytokine, capable of directly participating in the antiviral immune response of epithelial cells, mediating the natural immune response to induce the expression of Interferon Stimulated Genes (ISG), hence, swiftly establishing the body's natural immune defense line against viral infections.
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First Dosing of RGX-181 in a Pediatric CLN2 Patient's Initial Clinical Results Showcased at SSIEM Yearly Symposium
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First Dosing of RGX-181 in a Pediatric CLN2 Patient's Initial Clinical Results Showcased at SSIEM Yearly Symposium
2 September 2023
REGENXBIO Inc. shared the preliminary interim findings from a single-subject, researcher-led first-in-person study of RGX-181.
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Sirnaomics Announces Successful Phase I clinical trial for STP707, a RNAi therapeutic for addressing multiple solid tumors
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Sirnaomics Announces Successful Phase I clinical trial for STP707, a RNAi therapeutic for addressing multiple solid tumors
2 September 2023
A striking 74% of assessable patients showcased a premier response of steady disease.
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Initial Dose of ISA104 Administered to First Patient with Chronic Hepatitis B in Phase 1 Human Trials
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Initial Dose of ISA104 Administered to First Patient with Chronic Hepatitis B in Phase 1 Human Trials
2 September 2023
This inaugural human application (FIH) phase 1 examination, is exploring the efficiency of ISA104
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Alpine Immune Sciences Initiates Administration of 240mg IgA Nephropathy Group in Povetacicept Clinical Trial (RUBY-3)
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Alpine Immune Sciences Initiates Administration of 240mg IgA Nephropathy Group in Povetacicept Clinical Trial (RUBY-3)
2 September 2023
Alpine Immune Sciences, Inc., has revealed the successful launch of the second IgA nephropathy (IgAN) dosage group in RUBY-3, a phase 1b/2a
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Genexine's long-lasting growth hormone successfully reaches primary endpoint of Phase 3 trial
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Genexine's long-lasting growth hormone successfully reaches primary endpoint of Phase 3 trial
2 September 2023
Genexine,assessing the efficacy and security of eftansomatropin alfa (an exclusive long-acting growth hormone by Genexine, also referred to as GX-H9) in children suffering from growth hormone deficiency.
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BenevolentAI's Doses First Participants of BEN-8744; Targets PDE10
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BenevolentAI's Doses First Participants of BEN-8744; Targets PDE10
2 September 2023
BenevolentAI has now informed that its initial subjects have been administered in Phase I first-in-human trials of its oral phosphodiesterase 10 (PDE10) inhibitor, BEN-8744.
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