AbbVie, Futuregen sign IBD licensing deal

18 June 2024
AbbVie, a well-known pharmaceutical company, has recently entered into a global licensing agreement with Beijing-based FutureGen Biopharmaceutical. The focus of this collaboration is the development of FG-M701, a TL1A antibody designed to treat inflammatory bowel disease (IBD). As part of the agreement, AbbVie will take on the responsibilities for the development, manufacturing, and commercialization of FG-M701. In return, FutureGen will receive an upfront payment of $150 million, with potential milestone payments that could reach up to $1.56 billion. Additionally, FutureGen will earn royalties based on the net sales of the drug.

FG-M701 is currently in the preclinical development phase. The goal of this antibody is to target TL1A, aiming to improve the efficacy of existing treatments and reduce the frequency of dosing required. Both companies are optimistic that their collaboration will successfully advance FG-M701 through the necessary clinical trials and regulatory approval processes, ultimately providing a new treatment option for patients suffering from IBD.

This partnership with FutureGen is part of a broader strategy by AbbVie to expand its portfolio through strategic collaborations and acquisitions. Just last month, AbbVie entered into an option-to-license agreement with Gilgamesh Pharmaceuticals. This partnership aims to develop next-generation therapies for psychiatric disorders. As part of the deal, AbbVie provided Gilgamesh with $65 million upfront, and the agreement includes potential milestone payments that could total up to $1.95 billion.

These moves are indicative of AbbVie's aggressive investment strategy. Late last year, the company made headlines with two significant acquisitions. AbbVie spent $10.1 billion to acquire ImmunoGen, a specialist in ADC (antibody-drug conjugates) technology. Shortly after, they announced an $8.7 billion deal to acquire Cerevel Therapeutics, further expanding their reach into innovative therapeutic areas.

The strategic alliance with FutureGen Biopharmaceutical and the other recent deals underscore AbbVie's commitment to expanding its pipeline and bringing new, effective treatments to market. By focusing on partnerships and acquisitions, AbbVie is positioning itself to address unmet medical needs across various therapeutic areas, from inflammatory diseases like IBD to psychiatric disorders and beyond. The collaboration with FutureGen aims to leverage both companies' strengths to make FG-M701 a success, providing hope for improved treatment options for IBD patients worldwide.

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