First Nagoya-compliant GMP Iboga Extract, IBEX011, Available for Clinical and Academic Use

VANCOUVER, BC, May 20, 2024 – Terragnosis Inc., a Canadian company specializing in drug development, has unveiled IBEX011, the first Good Manufacturing Practice (GMP) extract of Tabernanthe iboga. This extract is now accessible for use in ibogaine clinics and academic studies. Notably, IBEX011 is the first ibogaine product to be compliant with the Nagoya Protocol, a United Nations treaty aimed at ensuring equitable benefits for traditional knowledge holders from the Bwiti tradition in Gabon.

Iboga root bark has been used for thousands of years in traditional healing and initiation ceremonies and has recently gained international attention for its application in treating drug addiction and neurological conditions, including traumatic brain injury. The world's largest medical ibogaine facility, Ambio Life Sciences, which treats over 50 patients monthly, will be the first clinic to administer Terragnosis' iboga extract to its patients.

Jonathan Dickinson, who serves as CEO of both Terragnosis and Ambio, commented, "This represents a sensible shift in our approach to producing psychedelic medicine. By reconnecting with the original source, we have fostered relationships with the most knowledgeable practitioners. Our aim is to provide a product with the most potent healing capabilities."

Unlike most ibogaine products currently available, which are produced semi-synthetically using chemicals from alternative plant sources, IBEX011 contains all the naturally occurring alkaloids found in Tabernanthe iboga root bark. This new extract is at least 30% more potent by weight than single-molecule ibogaine products.

"We've been taken aback by our findings thus far," said Trevor Millar, Co-Founder and Chief Operations Officer of Ambio. "We are eager to showcase the benefits of a standardized botanical like this for the healing and optimization of our patients."

The iboga used by Terragnosis is sourced from the A2E Association in Ebyeng, a Fang community in northeastern Gabon. The story of Aloïse Amougou, who decided to start planting iboga after his own initiation two decades ago, was highlighted in a 2023 feature article in National Geographic.

The strategic framework for Gabon's Nagoya Protocol compliance was developed and executed by Blessings of the Forest (BoTF), a non-profit committed to preserving and promoting Gabonese cultural and natural heritage. A2E is the first of 20 farms financed by BoTF. After ten years of effort, this initiative aims to establish a new standard for access and benefit-sharing in the fields of psychedelic production and the pharmaceutical industry.