Genprex to Present at 2024 BIO Convention

AUSTIN, Texas, May 30, 2024 - Genprex (NASDAQ: GNPX), a clinical-stage gene therapy firm specializing in innovative therapies for cancer and diabetes, is set to present its latest advancements at the upcoming 2024 BIO International Convention. Ryan Confer, the company's President, CEO, and CFO, will lead the presentation, scheduled for Monday, June 3, 2024, at 2:00 p.m. PT in Theater 1 of the San Diego Convention Center.

This event provides a platform for Genprex to highlight its pioneering gene therapies, with opportunities for attendees to engage in one-on-one discussions with Mr. Confer through the conference's scheduling system.

Genprex focuses on delivering transformative gene therapies for patients with cancer and diabetes, aiming to offer new treatment avenues for large patient populations with limited current options. The company collaborates with elite institutions to enhance its pipeline of innovative therapies. 

Central to Genprex's oncology efforts is the Oncoprex® Delivery System. This non-viral, systemic delivery method uses lipid-based nanoparticles to encapsulate gene-expressing plasmids. The intravenous administration targets tumor cells, prompting them to produce tumor suppressor proteins that are often deficient. The lead product in this category, Reqorsa® Immunogene Therapy (quaratusugene ozeplasmid), is undergoing evaluation in three trials for non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC), with each program receiving Fast Track Designation from the FDA. The SCLC program also benefits from an FDA Orphan Drug Designation.

For diabetes, Genprex employs a novel approach using an AAV vector to deliver Pdx1 and MafA genes directly to the pancreas. In Type 1 diabetes models, the therapy, designated GPX-002, transforms pancreatic alpha cells into beta-like cells capable of insulin production, potentially avoiding immune system attacks. For Type 2 diabetes, GPX-002 aims to rejuvenate and replace depleted beta cells.

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