Karyopharm Therapeutics Announces Inducement Grants per Nasdaq Rule 5635(c)(4)

13 June 2024

Karyopharm Therapeutics Inc., a notable pharmaceutical company based in Newton, Massachusetts, has revealed the allocation of restricted stock units (RSUs) to new team members. On May 31, 2024, the company granted 9,500 RSUs to three new employees as part of the Company's 2022 Inducement Stock Incentive Plan. This move is designed to entice new hires in line with Nasdaq's regulations.

Moreover, an impressive award of 200,000 RSUs was given to Dr. Michael Method, the Senior Vice President of Clinical Development. These stock units follow a vesting schedule over three years, with one-third of the shares vesting annually on the anniversary of the grant date. The continuous employment of the recipients at Karyopharm is a condition for the vesting of these RSUs. An exception allows for immediate full vesting if the employee's role is terminated without cause or for good reason within a year following a change in control event.

Karyopharm Therapeutics, trading on Nasdaq under KPTI, is celebrated for its innovative approach to cancer treatment. The company's pioneering work centers on the development of oral compounds that target nuclear export dysregulation, a key factor in cancer progression. Their flagship product, XPOVIO® (selinexor), an oral exportin 1 (XPO1) inhibitor, has received approval in the U.S. for three oncology indications. Additionally, it is marketed in various international markets, such as Europe, the UK (under the name NEXPOVIO®), and China.

Karyopharm’s research and development pipeline is robust, focusing on several high-need cancer areas. These include multiple myeloma, endometrial cancer, myelofibrosis, and diffuse large B-cell lymphoma (DLBCL). The company's commitment to leveraging scientific innovation is driven by a deep respect for the resilience and bravery of cancer patients.

XPOVIO® and NEXPOVIO® are trademarks registered by Karyopharm Therapeutics Inc., underscoring the company's proprietary innovations in the pharmaceutical industry.

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