Zentalis Pharmaceuticals to Speak at Jefferies Global Healthcare Conference

Zentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company listed on Nasdaq under the ticker ZNTL, has announced its participation in the upcoming Jefferies Global Healthcare Conference. The event is scheduled to take place on June 5, 2024, at 4:00 p.m. ET. During the conference, Zentalis management will engage in a fireside chat to discuss the company's progress and future prospects. Both live and archived versions of the webcast will be accessible on the "Events & Presentations" section of the company's official website.

Zentalis Pharmaceuticals focuses on discovering and developing small molecule therapeutics aimed at treating cancers by targeting fundamental biological pathways. The company's lead product candidate, azenosertib (ZN-c3), is a WEE1 inhibitor designed for the treatment of advanced solid tumors and hematologic malignancies. It is considered a potentially first-in-class and best-in-class drug in its category. Azenosertib is under evaluation both as a monotherapy and in combination with other treatments across multiple clinical trials, showcasing its broad potential.

Clinical trials have shown that azenosertib is well-tolerated and exhibits anti-tumor activity as a single agent in various tumor types. Additionally, it has demonstrated efficacy when combined with several chemotherapy regimens. To enhance the effectiveness of azenosertib, Zentalis is exploring enrichment strategies that target tumors with high genomic instability. These include Cyclin E1 positive tumors, homologous recombination deficient tumors, and tumors with oncogenic driver mutations.

Beyond azenosertib, Zentalis is also leveraging its expertise in cancer biology and medicinal chemistry to advance its research in protein degraders. This line of research aims to develop new treatments that can degrade cancer-causing proteins, offering another avenue for combating the disease.

Zentalis has operational bases in both New York and San Diego, which allows the company to take advantage of the diverse biopharmaceutical landscapes in these regions. The company continues to build on its extensive experience to bring innovative cancer treatments to market.

In conclusion, Zentalis Pharmaceuticals is making significant strides in the biopharmaceutical field with its lead product candidate, azenosertib. The company's participation in the Jefferies Global Healthcare Conference will provide an opportunity to share these advancements with a broader audience, enhancing its visibility and potentially attracting new investments.

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