Blue Toe Syndrome

Last update 01 Nov 2024

Basic Info

Synonyms

Blue Toe Syndrome, Blue Toe症候群, Blue toe syndrome

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Introduction

A condition that is caused by recurring atheroembolism in the lower extremities. It is characterized by cyanotic discoloration of the toes, usually the first, fourth, and fifth toes. Discoloration may extend to the lateral aspect of the foot. Despite the gangrene-like appearance, blue toes may respond to conservative therapy without AMPUTATION, SURGICAL.

100 Clinical Results associated with Blue Toe Syndrome

100 Translational Medicine associated with Blue Toe Syndrome

0 Patents (Medical) associated with Blue Toe Syndrome

220

Literatures (Medical) associated with Blue Toe Syndrome

31 Dec 2024·Future Science OA

Haloperidol-induced painless legs and moving toe syndrome in a schizophrenia patient: a case report

Author: Maheshwari, Mugundan U ; Sekar, Mahendran ; Shanmugasundaram, Natarajan ; Jeyabalan, Srikanth ; Sabarathinam, Sarvesh ; Begum, M Yasmin ; Wong, Ling S ; Sankar, Karthik

Painless legs and moving toe syndrome (PoLMT) is a rare syndrome characterized by involuntary movements of the toe without pain. The exact etiology of the patient's PoLMT is unknown. We present a case of PoLMT in 45-year-old woman with a history of haloperidol intake for 10 months. Haloperidol was discontinued, and aripiprazole (15 mg) was initiated. After this switch, a reduction in movement was observed in the third and fourth toes; however, the second toe showed no discernible change.

01 Dec 2024·Foot and Ankle Clinics

Orthotics for the Treatment of Lesser Toe Deformities

Review

Author: Orejana, Ángel M ; Monteagudo, Manuel ; Orejana, Ángel M.

Lesser toes play an important role in foot (and body) locomotion. Despite the high incidence of lesser toe disorders, their conservative treatments have rarely been studied. This study focuses on the conservative management of lesser toe deformities and will try to provide the reader with an overview on the portfolio of shoe modifications and orthotics available for the conservative treatment of lesser toe deformities, indication of each specific type of device, how they can impact on pain relief, and the rationale after considering conservative management as a first line of treatment and potentially avoiding surgery.

01 Jul 2024·JACC: Cardiovascular Interventions

Association Between Aortic Wall Thrombus and Thromboembolic Events After Transfemoral Transcatheter Aortic Valve Replacement

Article

Author: Lantelme, Pierre ; Boussel, Loïc ; Aktaa, Suleman ; Courand, Pierre-Yves ; Bonnet, Marc ; Bouali, Anissa ; Gerelli, Sébastien ; Ali, Noman ; Ricard, Cécile ; Lohse, Thomas ; Maxo, Ludovic ; Harbaoui, Brahim ; Mangin, Lionel

BACKGROUNDThromboembolic events, particularly strokes, remain a major complication of transcatheter aortic valve replacement (TAVR). Embolic protection devices have failed to show significant clinical benefit in large randomized clinical trials. Aortic wall thrombus (AWT) is often observed on multidetector computed tomography during TAVR work-up, but its prognostic significance is uncertain.OBJECTIVESThis study sought to evaluate the association between the presence of AWT and the incidence of thromboembolic outcomes in patients undergoing transfemoral (TF) TAVR for severe aortic stenosis.METHODSThis was a prospective cohort study of consecutive patients who underwent TF TAVR for severe aortic stenosis between January 2011 and April 2022. A dedicated scale (range: 0-10) was qualitatively used to assess AWT. The primary outcome was a composite of procedural thromboembolic events defined as ischemic stroke, blue toe syndrome, bowel ischemia, or other solid organ infarction. The secondary endpoints were ischemic strokes and procedural death.RESULTSOf the 641 patients included, severe AWT (score ≥8) was identified in 73 (11.4%). The presence of severe AWT was strongly associated with an increase in the primary outcome (OR: 8.48; 95% CI: 3.36-21.40; P < 0.001). This relationship persisted following multivariable analysis, which adjusted for comorbidities and procedural characteristics. The presence of severe AWT was also found to be associated with an increased incidence of stroke and procedural death (OR: 5.66; 95% CI: 2.00-15.30; P = 0.002 and OR: 4.66; 95% CI: 1.80-11.30; P = 0.002, respectively).CONCLUSIONSThe presence of severe AWT on preprocedural multidetector computed tomography is strongly associated with thromboembolic complications including stroke and mortality after TF TAVR.

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Blue Toe Syndrome

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