Last update 19 Sep 2024

Post-transplant lymphoproliferative disorder

Basic Info

Synonyms
Lymphoproliferative disorder following transplantation, Lymphoproliferative disorder following transplantation (disorder), PTLD
+ [15]
Introduction
Post-transplant lymphoproliferative disorder (PTLD) is a polyclonal (benign) or clonal (malignant) proliferation of lymphoid cells that develops as a consequence of immunosuppression in a recipient of a solid organ or bone marrow allograft. PTLDs comprise a spectrum ranging from early, Epstein-Barr virus (EBV)-driven polyclonal lymphoid proliferations to EBV-positive or EBV- negative lymphomas of predominantly B-cell or less often T-cell type. (WHO, 2001)

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