Meigs Syndrome

Last update 08 May 2025

Basic Info

Synonyms

Demons-Meigs syndrome, MEIGS SYNDROME, Meig Syndrome

+ [27]

Introduction

The triad of benign FIBROMA or other ovarian tumors with ASCITES, and HYDROTHORAX due to large PLEURAL EFFUSIONS.

Clinical Trials associated with Meigs Syndrome

NCT04618887

/ Unknown statusNot ApplicableIIT

A Comparative Study of GPI's DBS and Pallidotomy in the Treatment of Meige Syndrome

In this study, we will compare the degree of postoperative symptom improvement, postoperative complication rate, postoperative quality of life improvement degree of patients with Meige syndrome undergoing pallidotomy (unilateral globus palliotomy) and deep brain stimulation (unilateral globus pallidus) ,in order to get the conclusion of the comparison of the clinical efficacy of the two surgical plans. In addition, possible predictive factors such as age, gender, age of onset, length of disease course, scale baseline score, preoperative brain PET-CT function analysis and other possible predictive factors are added for analysis, in order to find predictive factors that can guide the choice of surgical options.

Start Date01 Jan 2020

Sponsor / Collaborator

Peking University People's Hospital

100 Clinical Results associated with Meigs Syndrome

100 Translational Medicine associated with Meigs Syndrome

0 Patents (Medical) associated with Meigs Syndrome

595

Literatures (Medical) associated with Meigs Syndrome

01 Jun 2025·Radiology Case Reports

Demons-Meigs syndrome: Rare cause of intraperitoneal and pleural effusion

Article

Author: Zaryouhi, Meryem ; Akammar, Amal ; Belhaj, Yassine ; Ouazzani Chahdi, Hajar ; Maaroufi, Mustapha ; Bouardi, Nizar El ; Ezzoulali, Zineb ; Lamrani, My Youssef Alaoui ; Boubbou, Meryem ; Chaouche, Ismail ; Melhouf, My Abdelilah ; Alami, Badr ; Akasbi, Imad ; Iraqui Houssaini, Elghali ; Ousrouti, Layla Tahiri

Demons-Meigs (DM) syndrome is characterized by the association of a benign ovarian tumor most often a fibroma or fibrothecoma with pleural and intraperitoneal effusions. It is a rare pathological entity. We report the case of a 40-year-old female patient with typical DM syndrome, characterized by the coexistence of pleural and intraperitoneal effusions, an ovarian mass, and a CA-125 level of 633 IU/ml. Laparotomy revealed abundant ascites and a large right ovarian mass, which was subsequently removed. Histopathological examination confirmed an ovarian fibroma. DM syndrome has a favorable prognosis, and treatment is primarily based on the removal of the ovarian tumor, without the need for chemotherapy or other therapeutic approaches.

01 Apr 2025·BMJ Case Reports

Meigs syndrome mimicking ovarian carcinoma: a diagnostic pitfall

Article

Author: Kapoor, Rohan ; Saha, Tejas ; Ray, Mukurdipi

Meigs syndrome, characterised by a pelvic mass, ascites and pleural effusion, is commonly associated with benign ovarian fibromas. It can mimic ovarian carcinoma both clinically and radiologically, leading to potential misdiagnosis. Early recognition of Meigs syndrome is crucial to prevent unnecessary interventions, such as chemotherapy or extensive surgery. This is a case summary of a woman in her early 50s who presented with abdominal pain, shortness of breath and a pelvic mass, suggestive of ovarian malignancy. Imaging and elevated CA-125 levels raised suspicion for ovarian cancer. However, histopathological examination of the mass revealed an ovarian fibroma, confirming Meigs syndrome. Meigs syndrome should be considered as part of the differential diagnosis in cases of pelvic masses with ascites and pleural effusion, helping to guide appropriate management and avoid unnecessary treatments.

01 Apr 2025·BMJ Case Reports

Pseudo-Meigs syndrome: a rare cause of abdominal ascites in a patient with an ovarian mass

Article

Author: Bowler, Taylor ; Dasaraju, Sandhyarani ; Thomson, Mary

Meigs syndrome is a rare phenomenon seen in approximately 1% of patients diagnosed with ovarian tumours. It is defined as a triad of a benign ovarian tumour, pleural effusion and ascites with complete resolution of symptoms following surgical intervention. This constellation of findings can be confused with several diagnoses, ranging from metastatic ovarian cancer to decompensated cirrhosis. Herein, we present a young woman presenting with new ascites, initially thought to be due to cirrhotic portal hypertension and found to have an atypical presentation of pseudo-Meigs syndrome, in the setting of a benign ovarian teratoma.

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Meigs Syndrome

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