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Last update 08 May 2025

Bronchopulmonary Sequestration

Last update 08 May 2025

Basic Info

Synonyms

BRONCHOPULMONARY SEQUESTRATION, Bronchopulmonary Sequestration, Bronchopulmonary Sequestrations

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Introduction

A developmental anomaly in which a mass of nonfunctioning lung tissue lacks normal connection with the tracheobroncheal tree and receives an anomalous blood supply originating from the descending thoracic or abdominal aorta. The mass may be extralobar, i.e., completely separated from normally connected lung, or intralobar, i.e., partly surrounded by normal lung.

Clinical Trials associated with Bronchopulmonary Sequestration

DRKS00036195

/ CompletedNot ApplicableIIT

The evaluation of success rates and complications of ultrasound controlled epidural anesthesia in a pediatric population from 2014 until 2024: An explorative, retrospective study in 1500 infants and children

Start Date14 Feb 2025

Sponsor / Collaborator-

ChiCTR2400090830

/ RecruitingNot ApplicableIIT

Incidence of hypercarbia during one-lung ventilation in infants with congenital pulmonary malformations

Start Date12 Oct 2024

Sponsor / Collaborator-

NCT06498583

/ RecruitingNot ApplicableIIT

Effect of Ultrasound-guided Erector Spinae Plane Block on Postoperative Pain and Sleep Quality of Infants With Congenital Pulmonary Cystic Disease After Thoracoscopic Surgery

This study intends to evaluate the effect of erector spinae plane block on postoperative analgesia and sleep quality in infants with congenital cystic pulmonary disease after thoracoscopic surgery, and provides reference for perioperative pain treatment in children.

Start Date05 Sep 2024

Sponsor / Collaborator

The Second Affiliated Hospital of Xi'an Jiaotong University

100 Clinical Results associated with Bronchopulmonary Sequestration

100 Translational Medicine associated with Bronchopulmonary Sequestration

0 Patents (Medical) associated with Bronchopulmonary Sequestration

2,428

Literatures (Medical) associated with Bronchopulmonary Sequestration

01 Jun 2025·Radiology Case Reports

Superselective transcatheter arterial embolization in the treatment of intra-abdominal extralobar pulmonary sequestration

Article

Author: Neto, Vivalde Faria Lobato ; Leite, Túlio Fabiano de Oliveira

Pulmonary sequestration is a congenital anomaly characterized by a mass of nonfunctioning lung parenchyma that receives a systemic arterial blood supply and is mainly located in the thorax. Intra-abdominal pulmonary sequestration, a rare subtype, is typically diagnosed within the first few months of life. We report the case of a term neonate with a history of recurrent left-sided pleural effusion requiring thoracentesis. A CT scan with venous contrast was performed, and an intrabdominal extralobar pulmonary sequestration was identified on the left, associated with a diaphragmatic hernia. The patient underwent embolization of the anomalous branch and reconstruction of the left diaphragm using bovine pericardium.

01 Jun 2025·SLAS Technology

The predictive value of chest CT combined with peripheral blood CD4/CD8 in patients with cerebral infarction complicated with pulmonary infection

Article

Author: Zhang, Jianhua ; Wu, Haojie ; Zheng, Jijing

To investigate the predictive value of chest computed tomography (CT) combined with peripheral blood CD4/CD8 in patients with cerebral infarction complicated with pulmonary infection. Lung consolidation, tree and bud sign, focus calcification ratio, C-reactive protein (CRP), procalcitonin (PCT), and interleukin-6 (IL-6) were significantly higher in the infected group than in the non-infected group, and CD4 and CD4/CD8 were significantly lower than in the non-infected group (P < 0.05). The results of stratified regression analysis showed that CRP, PCT, IL-6, lung consolidation, tree and bud sign, and calcification all had significant negative effects on CD4/CD8 (t=-5.875, -3.441, -10.406, -7.741, -3.977, -6.547, all P < 0.05). Lung consolidation, tree and bud signs, calcifications, elevated CRP, elevated PCT, and elevated IL-6 were risk factors for patients with pulmonary infection, and increased CD4/CD8 was a protective factor (P < 0.05). There was a non-linear dose-response relationship between CD4/CD8 and the risk of concurrent pulmonary infection (P_{non-linearity}=0.037), with a cut-off value of 0.98. The sensitivity, specificity, positive predictive value, and negative predictive value of combined diagnosis were significantly higher than CD4/CD8 (χ²=6.098, 4.640, 4.643, 6.076, P = 0.014, 0.031, 0.031, 0.014), and the area under the ROC curve of combined diagnosis was significantly higher than chest CT and peripheral blood CD4/CD8 (Z = 4.018, 5.112, P = 0.046, 0.037). Thoracic CT combined with peripheral blood CD4/CD8 can improve the diagnostic efficiency of cerebral infarction patients complicated with pulmonary infection and provide reference for clinical diagnosis and treatment.

15 Apr 2025·Journal of Chest Surgery

A Case of an Uncommon Cause of Pulmonary Abscess: Intralobar Bronchopulmonary Sequestration

Article

Author: Ireland, Max Edward ; O’Brien, Matthew ; Hollings, Nick ; Elzain, Osama

A patient in her early 20s presented with a cough and elevated inflammatory markers. A chest radiograph revealed an abnormal opacity in the right lower zone. Subsequent computed tomography showed an abscess in the right lower lobe that was fed by an anomalous vessel arising from the aorta. These findings were consistent with intralobar sequestration complicated by abscess formation. The patient was treated with antibiotics and discharged home, with plans for elective embolization and lobectomy under the care of the cardiothoracic surgeons. A literature review revealed a limited body of work on pulmonary sequestrations, with very few reported cases involving similar presentations. Thus, our case represents a rare and important addition to the literature.

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