Chondromatosis, Synovial

Last update 01 Nov 2024

Basic Info

Synonyms

Chondromatoses, Synovial, Chondromatosis, Synovial, Chondrometaplasia, Synovial

+ [42]

Introduction

Rare, benign, chronic, progressive metaplasia in which cartilage is formed in the synovial membranes of joints, tendon sheaths, or bursae. Some of the metaplastic foci can become detached producing loose bodies. When the loose bodies undergo secondary calcification, the condition is called synovial osteochondromatosis.

100 Clinical Results associated with Chondromatosis, Synovial

100 Translational Medicine associated with Chondromatosis, Synovial

0 Patents (Medical) associated with Chondromatosis, Synovial

1,409

Literatures (Medical) associated with Chondromatosis, Synovial

01 Oct 2024·Arthroscopy: The Journal of Arthroscopic & Related Surgery

Arthroscopic Chondral Nail Fixation for Treating Acetabular Cartilage Delamination Results in Improved Pain Relief at Minimum 2-year Follow-up in Patients with Femoroacetabular Impingement Syndrome: A Propensity-Matched Study

Article

Author: Zhang, Siqi ; Gao, Guanying ; Zhu, Yichuan ; Xu, Yan ; Liu, Zhenlong ; Liu, Jiayang ; Dong, Hanmei ; Du, Cancan ; Tian, Kang

PURPOSETo investigate the clinical outcomes following arthroscopic chondral nail fixation for acetabular cartilage delamination (ACD) in patients with femoroacetabular impingement syndrome (FAIS), and the presentation of ACD on MRI at follow-up.METHODSA retrospective review was performed between March 2021 and March 2022 at our institute. Patients undergoing primary hip arthroscopy for FAIS and diagnosed with ACD intraoperatively were included. Exclusion criteria were incomplete data or loss of minimum 2-year follow-up, and concomitant hip conditions including hip osteoarthritis with a Tönnis grade > 1, avascular necrosis, Legg-Calvé-Perthes disease, osteoid osteoma, synovial chondromatosis, pigmented villonodular synovitis, and developmental dysplasia of the hip (DDH). Patients who underwent chondral nail fixation were matched 1:1 with a control cohort of patients who only underwent simple debridement. Preoperative and minimum 2-year postoperative patient-reported outcome (PRO) scores including Visual Analog pain Scale (VAS), modified Harris Hip Score (mHHS), and percentage of achieving minimal clinically important difference (MCID) and patient acceptable symptom state (PASS) were collected and compared. MRI was performed preoperatively and at final follow-up to assess ACD.RESULTSFifty-eight patients were included in the study (29 patients in each group). Both groups demonstrated improved VAS and mHHS following surgery (all with P < .05). The chondral nail group demonstrated better postoperative VAS (P = .022) compared to the control group, while the postoperative mHHS was comparable between the two groups (P = .852). No significant difference was found in the achievement of MCID between the two groups (all with P > .05). More patients in the chondral nail group achieved PASS of VAS compared to the control group (75.9% vs 48.3%, P = .030). No patient underwent revision surgery or conversion to total hip arthroplasty (THA). The chondral nail group demonstrated significantly higher rate of ACD healing on MRI compared to the control group (P < .001).CONCLUSIONPatients undergoing arthroscopic chondral nail fixation for treating ACD demonstrated significant pain relief, more achievement of PASS of VAS, and higher rate of ACD healing on MRI compared to those undergoing simple debridement.LEVEL OF EVIDENCELevel III; retrospective cohort study.

13 Sep 2024·Cureus

Synovial Chondromatosis of the Knee Joint: Management With Arthroscopy-Assisted "Sac of Pebbles" Extraction and Synovectomy

Article

Author: Balasubramanian, Navin ; Vasudevan, Rajabalaji ; Ashraf, Munis ; Jayakaran, Harishbabu

Synovial chondromatosis is a rare, benign condition characterized by the formation of intra-articular cartilaginous loose bodies, which arise as a result of synovial membrane metaplasia. Due to pain, edema, and joint dysfunction, synovial chondromatosis can result in severe morbidity even though it is a self-limiting condition. In order to avoid problems, such as joint degeneration, early diagnosis and treatment is essential. This case study presents a female patient, age 24, who has experienced increasing pain, swelling, and occasional locking in her left knee for the past two years. Clinical examination of the suprapatellar pouch revealed several palpable loose bodies and effusion. Several intra-articular loose bodies were confirmed by imaging techniques. The patient underwent arthroscopic removal of multiple loose bodies and synovectomy. Histopathological examination confirmed the diagnosis as primary synovial chondromatosis. Postoperatively, the patient achieved a full range of movement without pain, and recurrence was not observed after three months of follow-up. For the treatment of knee synovial chondromatosis, an efficient and less invasive method is the arthroscopy-assisted removal of loose bodies and synovectomy. The value of this method in treating this uncommon condition is emphasized by the significant functional recovery and the lowered risk of recurrence.

28 Aug 2024·Cureus

A Rare Case of Synovial Chondromatosis in the Proximal Interphalangeal Joint of the Right Index Finger

Article

Author: Nair, Abhishek ; Chopra, Shubhankar ; Kumar, Sushant ; Reddy, Rajeev ; Phalak, Mukesh

Synovial chondromatosis is a rare condition that is also known as Reichel syndrome. It is a disorder that affects the monoarticular joints. The proliferation and metaplasia of the synovial cartilage are its defining characteristics. Many tiny, intra-articular osseocartilaginous loose bodies are formed as a result of this proliferation. They are fed by the synovial fluid once they break off from the synovial surface and enter the joint cavity, where they develop into calcification and ossification. If left untreated, it usually causes the afflicted joint to malfunction severely. Large joints such as the knee, hip, elbow, and shoulder joints are frequently the sites of nodular proliferation. Smaller joints such as the hand's interphalangeal and metacarpal joints and thumb are among the more unusual locations. Although the disease usually resolves on its own, conservative management options include painkillers, activity modification, and cryotherapy. Surgical options include synovectomy, which is the gold standard procedure and involves removing the loose bodies. The following case study presents a 60-year-old female patient with a rare instance of synovial chondromatosis. She presented to the outpatient department (OPD) due to escalating pain and swelling in the proximal interphalangeal (PIP) joint of her right index finger, which significantly restricted her range of motion. On the hand X-ray, several small, uniformly sized calcified bodies were visible within the synovium. After negative results from autoimmune disease tests, the patient was recommended for surgical exploration as the patient reported a six-month increase in pain and difficulty flexing his index finger. Surgical exploration of the PIP joint and adjacent proximal and middle phalanx revealed several small, evenly sized, firm, smooth, creamy-white nodules. Post-op, the patient was given a splint cast for a span of seven days, followed by physical therapy, and the range of motion was achieved by the end of six months.

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