Synonyms MSMD - mendelian susceptibility to mycobacterial disease, Mendelian Susceptibility to Mycobacterial Diseases, Mendelian susceptibility to mycobacterial disease + [3] |
Introduction A rare inherited disorder typically presenting in childhood characterized by a susceptibly to infection (local and disseminated), particularly from mycobacteria. This disorder has been associated with mutations in several genes including: IFNGR1, IFNGR2, STAT1, IL12B, IL12RB1, IRF8, ISG15, IKBKG, CYBB. |
Target |
Mechanism CD19 modulators [+2] |
Active Org.- |
Originator Org. |
Active Indication- |
Inactive Indication |
Drug Highest PhasePending |
First Approval Ctry. / Loc.- |
First Approval Date20 Jan 1800 |
Start Date01 Feb 2020 |
Sponsor / Collaborator ![]() [+1] |
Start Date20 Jun 2013 |
Sponsor / Collaborator |