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Last update 08 May 2025

Lymphocele

Last update 08 May 2025

Basic Info

Synonyms

Cyst of lymphatic tissue, Cyst of lymphatic tissue (disorder), Cyst, Lymphatic

+ [32]

Introduction

Cystic mass containing lymph from diseased lymphatic channels or following surgical trauma or other injury.

Drugs associated with Lymphocele

Lanreotide Acetate

Target

SSTR

Mechanism

SSTR antagonists

Active Org.

Ipsen Pharma SAS [+6]

Originator Org.

Ipsen Pharma Biotech SAS

Active Indication

Pituitary Neoplasms [+7]

Inactive Indication

Breast Cancer [+19]

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

China

First Approval Date14 Mar 2002

Clinical Trials associated with Lymphocele

NCT06258486

/ Not yet recruitingPhase 4

Ultrasound Guided Inguinal Indocyanine Green Injection to Identify and Pre-emptively Seal Lymphatic Leaks

Goal is to determine whether intraoperative ICG injection can be used to identify and reduce formation of symptomatic lymphoceles in patients receiving robot-assisted prostatectomy.

Start Date01 Feb 2024

Sponsor / Collaborator

Kaiser Permanente, Inc.

ChiCTR2100050155

/ SuspendedPhase 4IIT

Prospective, randomized, open and blank controlled clinical study of Jindan Fuyan granule in the treatment of lymphatic cyst (damp heat accumulation syndrome) after lymphadenectomy for endometrial or cervical cancer

Start Date01 Sep 2021

Sponsor / Collaborator

The Second Affiliated Hospital of Xi'an Jiaotong University

NCT04819542

/ RecruitingNot ApplicableIIT

Use of Compression Bandages in the Prevention of Post-mastectomy Lymphoceles

Lymphocele secondary to a mastectomy whether or not associated with a lymph node procedure (sentinel lymph node or axillary dissection) is an almost systematic consequence observed in the postoperative situation in this type of surgery.
This can be the source of pain, skin complications, and infection with a significant impact on the length of hospitalization for patients treated for breast cancer.
There is no consensus regarding the management of lymphocele. The placement of a compression bandage after mastectomy and / or axillary dissection would allow a more efficient and rapid reduction of the lymphocele and a reduction in recurrences.
This would make it possible to reduce the duration of the wearing of the drain, which determines the length of hospitalization and reduce the recurrence of lymphoceles, the punctures of which can be one of the risk factors for secondary lymphedema.

Start Date16 Aug 2021

Sponsor / Collaborator

Toulouse University Hospital

100 Clinical Results associated with Lymphocele

100 Translational Medicine associated with Lymphocele

0 Patents (Medical) associated with Lymphocele

2,396

Literatures (Medical) associated with Lymphocele

01 Jul 2025·Diagnostic Microbiology and Infectious Disease

First human case of infected lymphocele with bloodstream infection caused by Staphylococcus coagulans transmitted from a pet dog: a case report

Article

Author: Takemoto, Kenshiro ; Kobatake, Kohei ; Tadera, Kayoko ; Kohada, Yuki ; Sugai, Motoyuki ; Kitano, Hiroyuki ; Omori, Keitaro ; Hisatsune, Junzo ; Kitagawa, Hiroki ; Miyamoto, Shunsuke ; Ohge, Hiroki ; Tsunoi, Manami ; Hinata, Nobuyuki

We report the first case of a lymphocele and bloodstream infection caused by S. coagulans post-surgery. Single nucleotide polymorphism-based analyses revealed closely related S. coagulans isolates from the patient and his dog. Using whole genome sequencing, we demonstrated that S. coagulans was transmitted from a dog.

01 May 2025·General Thoracic and Cardiovascular Surgery

Lymphatic complication in open venous harvesting versus endoscopic venous harvesting: a systematic review and meta-analysis

Review

Author: Ahmadi, Ali ; Solati Kooshkqazi, Morteza ; Bahanesteh, Amirhossein ; Vanaki, Amirparsa ; Razavi, Alireza ; Fallah, Amirhossein ; Yarmohammadi, Hossein ; Mahalleh, Mehrdad ; Soltanipur, Masood

BACKGROUNDThe methods for saphenous vein (SV) harvesting include bridging vein harvesting (BVH), open vein harvesting (OVH), and endoscopic vein harvesting (EVH). Lymphatic complications, such as lymphatic leak, lymphedema, lymphangitis, and lymphocele, can arise following SV-harvesting surgery. This study aims to compare the incidence of lymphatic complications in SV harvesting using the OVH surgical method versus EVH.METHODSWe have systematically searched databases including Scopus, PubMed, and Web of Science until April 2024. Studies were considered eligible for inclusion if they performed SV harvesting and compared lymphatic complications in the EVH with OVH or BVH. Various lymphatic complications and follow-up periods were extracted. A meta-analysis was conducted comparing the relative risk (RR) of lymphatic complications in the EVH group versus the OVH group.RESULTSTwelve studies were included. A total of 1934 patients were involved and the majority were male. Follow-up times were from 6 days to 34 months. Results of the meta-analysis showed that the pooled lymphatic complications, lymphatic leak, and lymphedema are significantly higher in OVH versus EVH (RR = 6.78, p value < 0.01; RR = 17.33, p value < 0.01; RR = 8.88, p value < 0.01, respectively). No significant differences in lymphocele rates between the two methods (RR = 1.2, p value = 0.77). Both short-term and long-term follow-ups showed elevated lymphatic complication risks in OVH relative to EVH (RR = 4.91, p value < 0.01; RR = 30.27, p value = 0.03, respectively).CONCLUSIONEVH is linked to reduced rates of lymphatic complications. Also, OVH had a higher risk of lymphatic complications in the short and long term compared to EVH.

01 May 2025·Radiology Case Reports

Left subphrenic lymphocele after total gastrectomy

Article

Author: Elaitari, Khadija ; Jabour, Soukayna ; Boujida, Nadia ; Amalik, Sanae ; Omor, Youssef ; Latib, Rachida

Lymphocele, a collection of lymphatic fluid within a nonepithelialized cavity, is a rare surgical complication, most commonly associated with pelvic lymphadenectomy. It may also occur after other procedures involving lymphatic injury. We report the first documented case of a left subphrenic lymphocele following gastrectomy, identified via CT scan and confirmed by ultrasound. This case highlights its unique clinical and radiological features.

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