Last update 01 Nov 2024

Abortion, Incomplete

Last update 01 Nov 2024

Basic Info

Synonyms

Abortion spontaneous incomplete, Abortion spontaneous incomplete NOS, Abortion, Incomplete

+ [25]

Introduction

Premature loss of PREGNANCY in which not all the products of CONCEPTION have been expelled.

Clinical Trials associated with Abortion, Incomplete

NCT06456164 / Not yet recruitingNot ApplicableIIT

IntraCERvical Balloon Catheter in the Setting of Induction of Labor for Fetal Loss or Abortion (CERBI): a Pilot Randomized Controlled Trial

The goal of this research is to understand whether it is practical and safe to use an intracervical balloon catheter in addition to standard of care medications at the time of an induction of labor for an abortion or fetal death. The medical device used in this study is cleared by the Food and Drug Administration (FDA) and is used for induction of labor at term gestational ages (at or above 37 weeks of gestation). The study team will also collect data about patient-level experiences with the procedure, time in labor, and labor-related complications, such as higher-than-expected blood loss or infection.

Start Date01 Feb 2025

Sponsor / Collaborator

The University of Chicago

PACTR202409853980242 / RecruitingEarly Phase 1IIT

Comparing 2%Lignocaine and 2%Lignocaine with Hyoscine Butylbromide in Pain Reduction During Manual Vacuum Aspiration For Incomplete Abortion in Juth

Start Date01 Jun 2024

Sponsor / Collaborator-

ChiCTR2400090600 / RecruitingEarly Phase 1IIT

Analysis of the therapeutic effect of a combination drug regimen based on sequential therapy of estrogen and progesterone in the treatment of incomplete abortion

Start Date09 May 2024

Sponsor / Collaborator-

100 Clinical Results associated with Abortion, Incomplete

100 Translational Medicine associated with Abortion, Incomplete

0 Patents (Medical) associated with Abortion, Incomplete

801

Literatures (Medical) associated with Abortion, Incomplete

01 Nov 2024·European Journal of Obstetrics & Gynecology and Reproductive Biology

The HYsteroscopic Miscarriage MaNagement (HYMMN) pilot randomized-controlled trial

Article

Author: Justin Clark, T ; Sairally, B Zeyah F ; Coomarasamy, Arri ; Sairally, B. Zeyah F. ; Smith, Paul P ; Pickering, Oonagh ; De Silva, Prathiba M. ; O’Connor, Siobhan ; O'Connor, Siobhan ; Justin Clark, T. ; Smith, Paul P. ; Sairally, Zeyah ; De Silva, Prathiba M ; Woodhead, Natalie

OBJECTIVETo evaluate the feasibility of performing a full-scale, adequately powered, multi-center randomized controlled trial (RCT) assessing the effectiveness of office hysteroscopy (OH) for the treatment of retained pregnancy tissue (RPT) after miscarriage, compared with standard treatment (ST) (expectant/medical/surgical), on future pregnancy outcome.STUDY DESIGNSingle-center pilot RCT performed at Birmingham Women's Hospital, UK. Patients opting for non-surgical miscarriage management at ≤14 weeks gestation who wanted to conceive as soon as possible were recruited and offered a transvaginal ultrasound scan (TVUS) eight weeks later to check for the presence of RPT. Patients with RPT were randomized in a 1:1 ratio using a computer-generated online random allocation sequence to either OH (performed using the TruClear 5.0 hysteroscopic tissue retrieval system) or ST (the type of which was recommended based on symptoms, urinary pregnancy test and scan findings).RESULTS158 participants were approached for inclusion into the trial, of which 149 (94.3%) agreed. Of the 126 that underwent TVUS, RPT were diagnosed in 42 patients (33.3%). 21 patients were randomized to OH, of whom 18 underwent the procedure because three fell pregnant after their TVUS. OH was deemed acceptable to all patients without any serious complications. 21 patients were randomized to ST where 16 patients (76%) were recommended expectant management and five (24%) were recommended surgical management. 115 patients (91%) were able to provide pregnancy data, however, the study was not powered to show a clinically significant difference.CONCLUSIONA full-scale, adequately powered, randomized clinical trial investigating OH against ST for the treatment of RPT following miscarriage is clinically relevant and feasible owing to high rates of participation, acceptability and satisfaction and low rates of attrition associated with the proposed interventions.

01 Oct 2024·Clinical Case Reports

Omental incarceration secondary to uterine perforation after dilatation curettage: Conservative approach in sub‐saharan Africa

Article

Author: Kayar, Ilkan ; Bello, Fatthy ; Birge, Ozer

Key Clinical MessageComplications of uterine perforation and herniation of intra‐abdominal organs into the perforated area may occur after gynecological operations. They can be treated with a conservative approach, especially in cases whose vital signs are stable, laboratory values are within normal limits and their general condition is suitable. We aim to present the conservative treatment without using surgical and medical methods as it is the first case in the literature.AbstractUterine perforation is a rare but potentially serious complication of curettage for gynecologic or obstetric reasons especially during and after operative procedures and the application of intrauterine contraceptive devices. The incidence of uterine perforation during gynecological operations is between 0.002–1.7. A 30‐year‐old multiparous case with a 7‐week 4‐day pregnancy was diagnosed with incomplete abortion at an external center due to vaginal bleeding. The case underwent suction curettage. After 24 h, revision suction curettage was performed due to the finding of rest in the endometrium during the ultrasonographic control, and the case was diagnosed with uterine perforation and omental herniation due to this. We highlighted the importance of a thorough gynecological assessment following a dilated suction curettage (D&C) procedure that includes a careful clinical examination and a detailed ultrasound evaluation.

01 Oct 2024·Journal of International Medical Research

Spontaneous rupture of an unscarred uterus at the early third trimester due to placenta percreta: a case report

Article

Author: Hong, Xunyu ; Hong, Ling ; Zhang, Li

Uterine rupture during pregnancy is a complication of placenta percreta. We present the case of a woman in her early 30s with a history of incomplete abortion treated by dilatation and curettage who was admitted with abdominal pain and vomiting at 30 weeks of gestation. She was diagnosed with thrombophilia and was administered anticoagulant drugs. After 10 hours of monitoring, the patient abruptly deteriorated. An emergency cesarean delivery showed a ruptured uterus due to placenta percreta. She accepted localized excision and uterine repair, and recovered well. Rupture of an unscarred uterus due to placental percreta is an extremely rare obstetric complication with high maternal and fetal mortality. This condition should be suspected in all pregnant women who have severe abdominal pain without being in labor. The treatment of uterine rupture due to placental percreta should be individualized, and repair of the uterus is possible in the majority of women.

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Abortion, Incomplete

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