Livedo Reticularis

Last update 08 May 2025

Basic Info

Synonyms

ASPHYXIA RETICULARIS, LIVEDO ANNULARIS, LIVEDO RACEMOSA

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Introduction

A condition characterized by a reticular or fishnet pattern on the skin of lower extremities and other parts of the body. This red and blue pattern is due to deoxygenated blood in unstable dermal blood vessels. The condition is intensified by cold exposure and relieved by rewarming.

100 Clinical Results associated with Livedo Reticularis

100 Translational Medicine associated with Livedo Reticularis

0 Patents (Medical) associated with Livedo Reticularis

1,668

Literatures (Medical) associated with Livedo Reticularis

01 Apr 2025·JDDG: Journal der Deutschen Dermatologischen Gesellschaft

Occlusive cutaneous vasculopathies: rare differential diagnoses

Review

Author: Schneider, Stefan Werner ; Torster, Leopold Konstantin ; Hansen, Inga ; Burg, Maria Rosa

SummaryIn addition to erythematous plaques, nodules, ulcerations, and necrosis, retiform purpura and livedo racemosa are indications of occlusive cutaneous vasculopathies. In contrast to cutaneous vasculitis, occlusive cutaneous vasculopathies primarily lead to vascular occlusion of the skin and only secondarily to signs of vascular inflammation. The lower legs are typically affected, but especially in the presence of acral skin changes, occlusive cutaneous vasculopathies should also be considered. Various stimuli can trigger occlusive cutaneous vasculopathies, including systemic or vascular coagulopathies, emboli, platelet or erythrocyte aggregates, cold‐dependent gelling and agglutination of immunoglobulins, or, less commonly, medications.

01 Mar 2025·PRILOZI

Severe Complicated Secondary Antiphospholipid Syndrome Conjointly with Systemic Lupus Erythematosus – Case Report

Article

Author: Gucev, Filip ; Antova, Dubravka ; Sandevska, Emilija ; Vidinikj, Ivan ; Karadzova-Stojanovska, Anzelika ; Pavlova, Sonja ; Vasilevska, Ana ; Vejseli, Ron ; Bojadzioska, Maja ; Vidinikj, Sonja

AbstractAntiphospholipid syndrome (APS), is an autoimmune systemic disorder known to manifest with thrombosis in almost all vessels throughout the body, can also be accompanied by pregnancy morbidity, and is persistent with the presence of antiphospholipid antibodies, including lupus anticoagulant antibodies, or relatively high titers of anticardiolipin, or anti-β2Glycoprotein I antibodies. APS can occur alone or in association with other diseases, more commonly systemic lupus erythematous. In patients with both underlying diseases episodes of arthritis, skin changes in the form of livedo reticularis, thrombocytopenia and leucopenia were more common. Cardiac manifestations have also been reported. Here we present a complicated case of a young female patient with antiphospholipid syndrome and an underlying systemic lupus erythematosus.

01 Feb 2025·American Journal of Surgical Pathology

Sarcoid Vasculitis in the Skin

Article

Author: Nakajima, Hideki ; Chen, Ko-Ron ; Yamamoto, Toshiyuki ; Miura, Keiko ; Nakamura, Yoshio ; Takahashi, Hayato ; Inazumi, Toyoko

While the skin is a common target organ for sarcoidosis, cutaneous granulomatous vasculitis is rare among patients with sarcoidosis. Due to the lack of detailed studies on cutaneous sarcoid vasculitis, both dermatologists and pathologists remain unfamiliar with this rare but important vasculitic disorder. We clinicopathologically evaluated eight cases with biopsy-proven cutaneous vasculitis and cutaneous sarcoidosis and analyzed morphologic changes in the process of vasculitis for both small vessels and muscular vessels in detail. The various skin lesions ranged from papulonodular erythema, annular erythema, maculopapular erythema, livedo reticularis-like eruptions, erythema nodosum-like lesions, subcutaneous nodules to ulcerative lesions. The extremities were the most frequently affected sites. Bilateral hilar lymphadenopathy with pulmonary sarcoidosis was the most common extracutaneous comorbidity. Skin-limited sarcoidosis was identified in 3 cases. All cases demonstrated a common histopathologic feature with sarcoid granulomas impinging on the target vessels with resultant vessel destruction. Perivascular infiltration of sarcoid granulomas resulted in compression and destruction of small vessels. In muscular arteries and veins, sarcoid granulomas closely attached to the muscular vessel wall, infiltrated the muscular layers and either occupied or penetrated the vessel walls, eventually invading the vascular lumen and replacing the entire muscular layers. The intimal infiltration of sarcoid granulomas resulted in a marked luminal narrowing. The scarcity of reports on cutaneous sarcoid vasculitis may be due to the overlooking or misinterpretation of vascular destruction caused by sarcoid granuloma infiltration as a feature of sarcoid granuloma masses.

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Livedo Reticularis

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