Last update 19 Sep 2024
Slipped Capital Femoral Epiphyses
Last update 19 Sep 2024
Basic Info
Synonyms Adolescent Coxa Vara, Adolescent Coxa Varas, Bilateral Slipped Capital Femoral Epiphyses + [53] |
Introduction A developmental deformity in which the metaphysis of the FEMUR moves proximally and anteriorly away from FEMUR HEAD (epiphysis) at the upper GROWTH PLATE. It is most common in male adolescents and is associated with a greater risk of early OSTEOARTHRITIS of the hip. |
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100 Clinical Results associated with Slipped Capital Femoral Epiphyses
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100 Translational Medicine associated with Slipped Capital Femoral Epiphyses
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01 Mar 2024Resuscitation plus
Basic life support for non-traumatic out-of-hospital cardiac arrests during school-supervised sports activities in children: A nationwide observational study in Japan.
Article
Author: Kosuke Kiyohara ; Satoshi Matsui ; Mamoru Ayusawa ; Takeichiro Sudo ; Masahiko Nitta ; Taku Iwami ; Ken Nakata ; Yuri Kitamura ; Tomotaka Sobue ; Tetsuhisa Kitamura ; SPIRITS investigators
Objective:
To investigate the prognostic impact of bystander-initiated cardiopulmonary resuscitation (CPR) and public-access automated external defibrillator (AED) use on non-traumatic out-of-hospital cardiac arrest (OHCA) occurring during school-supervised sports activities in children.
Methods:
From a nationwide database of pediatric OHCAs occurring under school supervision in Japan, data between April 2008 and December 2020 were obtained. We analyzed non-traumatic OHCAs that occurred during school-supervised sports activities among schoolchildren from elementary, junior high, high, and technical colleges. A multivariable logistic regression model was used to evaluate the effect of basic life support (BLS) on 1-month survival with favorable neurological outcomes after OHCA.
Results:
In total, 318 OHCA cases were analyzed. The 1-month survival with favorable neurological outcomes was 64.8% (164/253) in cases receiving both bystander-CPR and AED application, 40.7% (11/27) in cases receiving CPR only, 38.5% (5/13) in patients receiving AED application only, and 28.0% (7/25) in cases receiving no bystander intervention. Compared with cases receiving no BLS, cases receiving both CPR and AED had a significantly higher proportion of 1-month survival with favorable neurological outcomes (adjusted odds ratio [AOR]: 3.97, 95% confidence interval [CI]: 1.32-11.90, p = 0.014). However, compared to cases receiving no BLS, there was no significant difference in the outcome in the cases receiving CPR only (AOR: 1.35, 95% CI: 0.34-5.29, p = 0.671) and the cases receiving AED application only (AOR: 1.26, 95% CI: 0.25-6.38, p = 0.778).
Conclusion:
The combination of CPR and AED as BLS performed by bystanders for non-traumatic OHCA during school-supervised sports activities improved the outcomes.
20 Feb 2024Scientific reports
The efficacy of Denosumab in the treatment of femoral head osteonecrosis: a retrospective comparative study.
Article
Author: Jun-Ki Moon ; Jinyong Park ; Yisack Yoo ; Jae Youn Yoon ; Sunhyung Lee ; Pil Whan Yoon
The present study aimed to compare clinical and radiological differences of ONFH patients who were treated with denosumab, and a control group. A total of 178 patients (272 hips) with symptomatic, nontraumatic ONFH were divided into a denosumab group (98 patients, 146 hips) and a control group (80 patients, 126 hips). Patients in the denosumab group received a 60 mg subcutaneous dose of denosumab every 6 months. For the clinical assessments, Harris hip scores (HHS), Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were evaluated. Plain radiographs and MRI were performed before and a minimum of 1 year after administration of denosumab, which were evaluated for radiological results including femoral head collapse (≥ 2 mm) and volume change of necrotic lesion. Femoral head collapse occurred in 36 hips (24.7%) in the denosumab group, and 48 hips (38.1%) in the control group, which was statistically significant (P = 0.012). Twenty-three hips (15.8%) in the denosumab group and 29 hips (23%) in the control group required THA, which showed no significant difference (P = 0.086). At the final follow-up, 71.9% of hips in the denosumab group had a good or excellent HHS compared with 48.9% in the control group, showing a significant difference (P = 0.012). The denosumab group showed a significantly higher rate of necrotic lesion volume reductions compared with the control group (P < 0.001). Denosumab can significantly reduce the volume of necrotic lesions and prevent femoral head collapse in patients with ARCO stage I or II ONFH.
19 Feb 2024Journal of pediatric orthopedics
Letter to the Editor: The Effect of Human Growth Hormone Treatment on the Development of Slipped Capital Femoral Epiphysis-A Cohort Analysis With 6 Years of Follow-Up.
Article
Author: Zhikang Tian ; Zichun Wei ; Jiahui Wang ; Chunyang Meng
Analysis
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