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Last update 23 Jan 2025

Villous Adenoma

Last update 23 Jan 2025

Basic Info

Synonyms

ADENOMA VILLOUS, Adenoma, Villous, Adenomas, Villous

+ [21]

Introduction

An adenoma of the large intestine. It is usually a solitary, sessile, often large, tumor of colonic mucosa composed of mucinous epithelium covering delicate vascular projections. Hypersecretion and malignant changes occur frequently. (Stedman, 25th ed)

Clinical Trials associated with Villous Adenoma

NCT02306707

/ RecruitingNot ApplicableIIT

Outcomes of Endoscopic Resection of Mucosal and Submucosal Lesions in the Stomach.

A patient referred to have a lesion in the stomach removed. The aims of this study are to collect information on the technique of endoscopic removal of such lesions. By collecting information on a large number of patients undergoing this procedure the investigators can determine the best ways of diagnosing and removing these lesions safely and effectively.

Start Date01 Oct 2014

Sponsor / Collaborator

Western Sydney Local Health District

NCT02306603

/ RecruitingNot ApplicableIIT

Outcomes of Endoscopic Resection of Mucosal and Submucosal Lesions in the Duodenum and Ampulla

This research project, 'Outcomes of endoscopic resection of mucosal and submucosal lesions in the duodenum and ampulla'. The research project is aiming to determine the most effective and safe way to remove such lesions.

Start Date01 Oct 2014

Sponsor / Collaborator

Western Sydney Local Health District

NCT02305290

/ RecruitingNot ApplicableIIT

Outcomes of Endoscopic Resection in the Upper Gastrointestinal Tract

The purpose of this study is to evaluate the long-term outcomes of Endoscopic Resection (ER) of superficial lesions of the Upper Gastrointestinal Tract(UGIT)

Start Date01 Aug 2014

Sponsor / Collaborator

Western Sydney Local Health District

100 Clinical Results associated with Villous Adenoma

100 Translational Medicine associated with Villous Adenoma

0 Patents (Medical) associated with Villous Adenoma

1,952

Literatures (Medical) associated with Villous Adenoma

01 Apr 2025·DEN Open

A case of intraductal papillary neoplasm of the bile duct suspected to be of peribiliary glands origin

Article

Author: Arai, Yoshifumi ; Naito, Takehito ; Suzuki, Hirotaka ; Ogiso, Takuya ; Yamada, Masahiro ; Yamamoto, Hideko ; Urano, Fumihiro ; Aoba, Taro ; Matsubara, Hiroshi ; Hattori, Shun

AbstractPeribiliary glands are complex lobular structures containing mucus and serous glands, distributed along the extrahepatic and intrahepatic bile ducts. In this report, we describe a case of intraductal papillary neoplasm of the bile duct suspected to be of peribiliary glands origin. The patient was an 80‐year‐old man who was referred to our hospital for a hepatic mass. On further examination, a 38 × 34 mm cystic lesion with papillary growth was found in S1/4. Because the lesion was extensively bordered by both hepatic ducts and the connection was unclear, it was difficult to determine the extent of hepatic resection. To confirm the location, a peroral cholangioscopy was performed. The connection with the cyst was detected in the right hepatic duct and a villous tumor mucosa protruded through the conduit lumen. Since we found that the lesion communicated with the right hepatic duct, a right hepatectomy was subsequently performed. The postoperative pathological diagnosis was an intraductal papillary neoplasm of the blie duct with associated invasive carcinoma. The postoperative course was good, and the patient experienced no recurrence.

01 Apr 2025·DEN Open

Balloon catheter‐assisted endoscopic resection for papillary adenoma of non‐exposed protruded type (with video)

Article

Author: Gu, Weigang ; Jin, Hangbin ; Zhang, Xiaofeng ; Yang, Jianfeng ; Tan, Justin Ryan L. ; Cheung, Ka Shing ; Tang, Chuang ; Lou, Qifeng

AbstractPapillary adenomas, known precursors to papillary adenocarcinoma, warrant close monitoring due to their malignant potential. Historically, surgical resection represented the mainstay of treatment for papillary adenomas with intraductal extension. However, recent advancements in endoscopic techniques have facilitated the adoption of endoscopic papillectomy as a minimally invasive alternative in carefully selected cases. We report a case of an 82‐year‐old woman with a diagnosis of papillary adenoma exhibiting intraductal extension. This was managed with a novel endoscopic technique, balloon catheter‐assisted endoscopic resection. Due to the obscured intraductal component of the papillary mass, a balloon occlusion catheter was deployed within the common bile duct and used as traction to facilitate endoscopic visualization of the mass. Endoscopic resection via papillectomy was subsequently performed. Histopathological examination of the resected specimen revealed a villous adenoma with high‐grade dysplasia. Serial endoscopic ultrasound examinations with targeted papillary biopsies were performed to monitor for disease recurrence.

01 Jan 2025·Placenta

Placental pathology of IVF-conceived dichorionic diamniotic twins after fresh embryo versus frozen-thawed transfer

Article

Author: Livoff, Alejandro ; Shlush, Ekaterina ; Aiob, Ala ; Sgayer, Inshirah ; Hammudi, Rudi ; Mikhail, Susana Mustafa ; Lowenstein, Lior ; Sarhan, Talal

INTRODUCTIONTo compare histopathological findings of placentas of dichorionic diamniotic twin pregnancies of in-vitro fertilization (IVF), conceived after fresh embryo transfer (ET) and frozen-thawed ET.METHODSThis retrospective study compared dichorionic diamniotic twin IVF pregnancies that resulted in livebirths during 2010-2022. The placental findings were classified according to definitions curated by the 2016 Amsterdam Placental Workshop Group Consensus Statement. A multivariate logistic analysis was constructed to estimate the odds ratios (OR) of placental histopathology abnormal findings, adjusted for maternal age, body mass index and nulliparity.RESULTSThe mean gestational age at birth was lower following fresh ET pregnancies (n = 236) than frozen-thawed ET pregnancies (n = 122) (34.89 vs 35.77 weeks, p = 0.003). For the fresh ET compared to the frozen-thawed ET group, rates were higher of preterm birth (69.5 % vs. 55.7 %, p = 0.011), low birthweight (71.6 % vs 57.4 %, p < 0.001) and very low birthweight (14.2 % vs 9.0 %, p value one sided = 0.029). For the fresh ET compared with the frozen-thawed ET group, the rates were higher of maternal vascular lesions (20.3 % vs. 11.5 %, p = 0.003), placental hemorrhage (12.7 % vs. 7 %, p = 0.021), and villous lesions related to maternal vascular lesions (7.2 % vs. 3.7 %, p value one sided = 0.04). A multivariate logistic analysis showed a higher risk of maternal or neonatal vascular lesions for twin pregnancies after fresh ET than frozen-thawed ET (adjusted OR = 1.91, 95 % CI 1.26-2.92, p = 0.011).CONCLUSIONSFollowing fresh ET compared to frozen-thawed ET, obstetrical and neonatal outcomes were worse, and the risk of maternal vascular lesions was greater.

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Villous Adenoma

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