Last update 01 Nov 2024

Gastroptosis

Last update 01 Nov 2024

Basic Info

Synonyms

Gastric prolapse, Gastroptosis, Gastroptosis (disorder)

+ [11]

Introduction-

Drugs associated with Gastroptosis

Lamb's Tripe Extract/Vitamin B12

Target-

Mechanism-

Active Org.

Xinjiang Biochemical Pharmaceutical Co., Ltd.

Originator Org.

Xinjiang Biochemical Pharmaceutical Co., Ltd.

Active Indication

Chronic gastritis [+2]

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date01 Jan 1996

Fuling Yin

Target-

Mechanism-

Active Org.

Kotaro pharmaceutical Co Ltd.

Originator Org.

Kotaro pharmaceutical Co Ltd.

Active Indication

Anorexia [+5]

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date30 Oct 1986

Liujunzi Decoction

Target-

Mechanism-

Active Org.

Sanwa Shoyaku Co., Ltd. [+1]

Originator Org.

Sanwa Shoyaku Co., Ltd.

Active Indication

Anorexia [+6]

Inactive Indication-

Drug Highest PhaseApproved

First Approval Ctry. / Loc.

First Approval Date18 Jul 1986

Clinical Trials associated with Gastroptosis

ChiCTR2100044168 / RecruitingEarly Phase 1IIT

Clinical study on the treatment of gastric mucosal prolapse with endoscopic mucosal ligation

Start Date01 Mar 2021

Sponsor / Collaborator-

JPRN-jRCT1080225055 / RecruitingNot Applicable

Adverse Drug Reaction Frequency Investigation of TSUMURA Hochuekkito Extract Granules for Ethical Use

Start Date07 Feb 2020

Sponsor / Collaborator

Tsumura & Co.

JPRN-JapicCTI-163267 / CompletedNot Applicable

Adverse Drug Reaction Frequency Investigation of TSUMURA Rikkunshito Extract Granules for Ethical Use

Start Date01 Jun 2016

Sponsor / Collaborator

Tsumura & Co.

100 Clinical Results associated with Gastroptosis

100 Translational Medicine associated with Gastroptosis

0 Patents (Medical) associated with Gastroptosis

289

Literatures (Medical) associated with Gastroptosis

01 Sep 2024·Journal of Clinical and Experimental Hepatology

Successful Surgical Management of Giant Mucinous Cystic Neoplasm of Liver (MCN-L) Presenting With Peritoneal Rupture and Biliary Prolapse: Case Report and Review of Literature

Article

Author: Aggarwal, Bharat ; Saigal, Sanjiv ; Rastogi, Ruchi ; Luthra, Rohan ; Agarwal, Riti ; Gupta, Subhash ; Kumar, Mukesh

Mucinous cystic neoplasms of liver (MCN-L) are generally considered benign indolent cystic liver lesions, not associated with significant clinical symptoms in majority of patients. However, rarely these benign-appearing lesions may have a complicated clinical course, presenting with jaundice, acute abdomen, or malignant transformation. We report one such rare clinical presentation of MCN-L presenting with obstructive jaundice and abdominal pain due to prolapse of cystic component in biliary system and peritoneal rupture occurring simultaneously. Despite the complex nature of presentation, it was successfully managed surgically with normal follow-up imaging.

01 Sep 2024·Digestive and Liver Disease

A deep learning model based on magnifying endoscopy with narrow-band imaging to evaluate intestinal metaplasia grading and OLGIM staging: A multicenter study

Article

Author: Liu, Leheng ; Niu, Wenlu ; Wu, Yulun ; Mao, Tiancheng ; Wu, Xiaowan ; Yuan, Lin ; Dong, Zhixia ; Chen, Congying ; Bu, Xiongzhu ; Zhou, Hui ; Yao, Fanghao ; Wang, Jing ; Wan, Xinjian

BACKGROUND AND PURPOSEPatients with stage III or IV of operative link for gastric intestinal metaplasia assessment (OLGIM) are at a higher risk of gastric cancer (GC). We aimed to construct a deep learning (DL) model based on magnifying endoscopy with narrow-band imaging (ME-NBI) to evaluate OLGIM staging.METHODSThis study included 4473 ME-NBI images obtained from 803 patients at three endoscopy centres. The endoscopic expert marked intestinal metaplasia (IM) regions on endoscopic images of the target biopsy sites. Faster Region-Convolutional Neural Network model was used to grade IM lesions and predict OLGIM staging.RESULTSThe diagnostic performance of the model for IM grading in internal and external validation sets, as measured by the area under the curve (AUC), was 0.872 and 0.803, respectively. The accuracy of this model in predicting the high-risk stage of OLGIM was 84.0%, which was not statistically different from that of three junior (71.3%, p = 0.148) and three senior endoscopists (75.3%, p = 0.317) specially trained in endoscopic images corresponding to pathological IM grade, but higher than that of three untrained junior endoscopists (64.0%, p = 0.023).CONCLUSIONThis DL model can assist endoscopists in predicting OLGIM staging using ME-NBI without biopsy, thereby facilitating screening high-risk patients for GC.

01 Jun 2024·Otolaryngologic Clinics of North America

Surgical Management of Pediatric Obstructive Sleep Apnea Beyond Tonsillectomy & Adenoidectomy

Review

Author: Maksimoski, Matthew ; Li, Carol

Pediatric patients with persistent obstructive sleep apnea (OSA) after adenotonsillectomy often have additional sites of upper airway obstruction such as the tongue base or larynx. Sleep endoscopy and cross-sectional, dynamic imaging can be used to direct surgical management of persistent OSA. The tongue base is one of the most common sites of obstruction in children with persistent OSA, especially for patients with Trisomy 21. Lingual tonsillectomy, tongue suspension, and/or posterior midline glossectomy may be used to address lingual tonsil hypertrophy and tongue base obstruction. Epiglottopexy and/or supraglottoplasty may be used to address laryngomalacia and epiglottic prolapse resulting in OSA.

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Gastroptosis

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