Synonyms Degenerated intervertebral disc, Degeneration of intervertebral disc, Degeneration of intervertebral disc (disorder) + [72] |
Introduction Degenerative changes in the INTERVERTEBRAL DISC due to aging or structural damage, especially to the vertebral end-plates. |
Mechanism Chondroitin sulfate proteoglycans modulators [+1] |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication- |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. JP |
First Approval Date23 Mar 2018 |
Target- |
Mechanism Cell replacements |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. NZ |
First Approval Date25 May 2012 |
Target |
Mechanism BMPR1A stimulants |
Active Org. |
Originator Org. |
Active Indication |
Inactive Indication |
Drug Highest PhaseApproved |
First Approval Ctry. / Loc. EU [+3] |
First Approval Date09 Sep 2002 |
Start Date09 Sep 9999 |
Sponsor / Collaborator- |
Start Date01 Nov 2025 |
Sponsor / Collaborator |
Start Date30 Sep 2025 |
Sponsor / Collaborator |