ZHB-111

Main purpose: To explore the efficacy, safety, tolerability, PK/PD characteristics and immunogenicity of different doses of QHRD211 injection in the treatment of growth disorders in children caused by endogenous growth hormone deficiency, explore the relationship between dosage, dosing interval, blood drug concentration and dose effect, and determine the usage and dosage of Phase III clinical trials. Secondary purpose: To compare the efficacy, safety and PK/PD characteristics of QHRD211 injection, recombinant human growth hormone injection (Saizen) and polyethylene glycol recombinant human growth hormone injection (Jinsaizen). Exploratory purpose: To evaluate whether QHRD211 injection has beneficial effects on the target population in the following ways: 1) Improve the treatment compliance of the subjects. 2) Reduce the disease burden on the family of the subjects.