Last update 08 Nov 2024

JYB-1907

Overview

Basic Info

Drug Type
Monoclonal antibody
Synonyms
JYB 1907, JYB-1907, JYB1907
Target
LRRC32 x TGF-β1
Mechanism
LRRC32 inhibitors(Transforming growth factor beta activator LRRC32 inhibitors), TGF-β1 inhibitors(Transforming growth factor beta 1 inhibitors)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid NeoplasmSolid tumor
Inactive Indication-
Originator Organization
Jiangxi Jemincare Group Co., Ltd.Jiangxi Jemincare Group Co., Ltd.
Active Organization
Jemincare Therapeutics Corp.Shanghai Jiyu Medical Technology Co., Ltd.Jiangsu Jiye Biopharmaceutical Co., Ltd.Startup
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with JYB-1907
CTR20231895 / RecruitingPhase 1
评价注射用JYB1907在晚期恶性实体瘤患者中的安全性、耐受性、药代动力学和初步有效性的多中心、开放、剂量递增和扩展队列Ⅰ期临床研究
[Translation] A multicenter, open-label, dose-escalation and expansion cohort Phase I clinical study to evaluate the safety, tolerability, pharmacokinetics and preliminary efficacy of JYB1907 for injection in patients with advanced malignant solid tumors
NCT05821595 / Not yet recruitingPhase 1
A Phase I, Multi-center, Open-label Study With Dose-escalation and Multiple Expansion Cohorts to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of JYB1907 in Subjects With Advanced Solid Tumors
100 Clinical Results associated with JYB-1907
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100 Translational Medicine associated with JYB-1907
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100 Patents (Medical) associated with JYB-1907
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100 Deals associated with JYB-1907
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1-
Jemincare Therapeutics Corp.
31 Jul 2023
Solid tumorPhase 1
US
Shanghai Jiyu Medical Technology Co., Ltd.
04 Jan 2023
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Clinical Result

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Approval

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Regulation

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