Last update 15 Dec 2025

ISM-4808

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ISM 4808, ISM-4808, ISM4808
Target
EGLN2 x PHD2
Action
inhibitors
Mechanism
EGLN2 inhibitors(egl-9 family hypoxia inducible factor 2 inhibitors), PHD2 inhibitors(egl-9 family hypoxia inducible factor 1 inhibitors)
Therapeutic Areas
Hemic and Lymphatic Diseases
Active Indication
Anemia of renal disease
Inactive Indication-
Originator Organization
Insilico Medicine Shanghai LtdInsilico Medicine Shanghai Ltd
Active Organization
Insilico Medicine Shanghai LtdInsilico Medicine Shanghai Ltd
Inactive Organization-
License Organization
Taigen Biopharmaceuticals Co. (Beijing), Ltd.Taigen Biopharmaceuticals Co. (Beijing), Ltd.TaiGen Biotechnology Co., Ltd.TaiGen Biotechnology Co., Ltd.InSilico Medicine, Inc.
Drug Highest PhaseIND Approval
First Approval Date-
Regulation-
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Related

100 Clinical Results associated with ISM-4808
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100 Translational Medicine associated with ISM-4808
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100 Patents (Medical) associated with ISM-4808
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100 Deals associated with ISM-4808
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Anemia of renal diseaseIND Approval
China
Insilico Medicine Shanghai LtdInsilico Medicine Shanghai Ltd
22 Aug 2023
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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