Last update 08 May 2025

Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Dactavira Plus, EPGCG//Sofosbuvir/Daclatasvir/Ribavirin
Target
IMPDH x NS5A x NS5B polymerase x RNAP x RNGTT
Action
inhibitors
Mechanism
IMPDH inhibitors(Inosine-5'-monophosphate dehydrogenase (IMPDH) inhibitors), NS5A inhibitors(Nonstructural protein 5A inhibitors), NS5B polymerase inhibitors(Hepatitis C virus NS5B RNA-dependent RNA polymerase inhibitors)
+ [2]
Therapeutic Areas
Infectious DiseasesDigestive System Disorders
Active Indication-
Inactive Indication
Hepatitis C
Originator Organization-
Active Organization-
Inactive Organization
The Egyptian Liver Research Institute And Hospital
License Organization-
Drug Highest PhasePendingPhase 3
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC8H12N4O5
InChIKeyIWUCXVSUMQZMFG-AFCXAGJDSA-N
CAS Registry36791-04-5
View All Structures (4)

Related

1
Clinical Trials associated with Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin
NCT03186313
/ CompletedPhase 3IIT
A Phase 3 Randomized, Open-Label, Study to Evaluate the Safety and Efficacy of the Combined Single Dose of Dactavira Plus (EPGCG, Sofosbuvir , Daclatasvir & Ribavirin) Versus Sofosbuvir + Daclatasvir + Ribavirin (Part A) and a Single Dose of Dactavira (EPGCG, Sofosbuvir & Daclatasvir) Versus Sofosbuvir + Daclatasvir (Part B) in Egyptian Adults With Chronic Genotype 4 HCV Infection
100 Clinical Results associated with Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin
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100 Translational Medicine associated with Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin
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100 Patents (Medical) associated with Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin
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100 Deals associated with Epigallocatechin Gallate/Sofosbuvir/Daclatasvir/Ribavirin
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Hepatitis CPhase 3
Egypt
The Egyptian Liver Research Institute And Hospital
01 Sep 2016
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

No Data

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Clinical Trial

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Approval

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Regulation

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