Last update 08 May 2025

Uprosertib/Trametinib Dimethyl Sulfoxide

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms-
Target
Akt-1 x Akt-2 x Akt-3 x MEK1 x MEK2
Action
inhibitors
Mechanism
Akt-1 inhibitors(Serine/threonine-protein kinase AKT1 inhibitors), Akt-2 inhibitors(Serine/threonine-protein kinase AKT2 inhibitors), Akt-3 inhibitors(Serine/threonine-protein kinase AKT3 inhibitors)
+ [2]
Therapeutic Areas
NeoplasmsHemic and Lymphatic DiseasesUrogenital Diseases
Active Indication
Acute Myeloid LeukemiaEndometrial CarcinomaUterine Cervical Cancer
Inactive Indication-
Originator Organization
Novartis Pharma AG
Active Organization
Novartis Pharma AG
Inactive Organization-
License Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Structure/Sequence

Molecular FormulaC18H16Cl2F2N4O2
InChIKeyAXTAPYRUEKNRBA-JTQLQIEISA-N
CAS Registry1047634-65-0
View All Structures (2)

Related

100 Clinical Results associated with Uprosertib/Trametinib Dimethyl Sulfoxide
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100 Translational Medicine associated with Uprosertib/Trametinib Dimethyl Sulfoxide
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100 Patents (Medical) associated with Uprosertib/Trametinib Dimethyl Sulfoxide
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100 Deals associated with Uprosertib/Trametinib Dimethyl Sulfoxide
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Acute Myeloid LeukemiaPhase 2-
Novartis Pharma AG
-
Endometrial CarcinomaPhase 2-
Novartis Pharma AG
-
Uterine Cervical CancerPhase 2-
Novartis Pharma AG
-
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Deal

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Core Patent

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Clinical Trial

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Approval

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Regulation

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