Last update 31 Mar 2025

BR-115

Overview

Basic Info

Drug Type
Trispecific T-cell engager (TriTE)
Synonyms
BR 115, BR-115, BR115
+ [1]
Target
CD19 x CD20 x CD3 x HER2
Action
modulators, stimulants
Mechanism
CD19 modulators(B-lymphocyte antigen CD19 modulators), CD20 modulators(B-lymphocyte antigen CD20 modulators), CD3 stimulants(T cell surface glycoprotein CD3 stimulants)
Therapeutic Areas
Neoplasms
Active Indication
Advanced Malignant Solid Neoplasm
Inactive Indication-
Originator Organization
Chengdu Chimagen Biosciences Co. Ltd.Chengdu Chimagen Biosciences Co. Ltd.
Active Organization
BioRay Biopharmaceutical Co., Ltd.BioRay Biopharmaceutical Co., Ltd.Chengdu Chimagen Biosciences Co. Ltd.Chengdu Chimagen Biosciences Co. Ltd.
Inactive Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with BR-115
NCT06388902
/ Not yet recruitingPhase 1
A Phase I Clinical Study of the Safety, Tolerability and Efficacy of BR115 for Injection in Patients With Advanced Solid Malignancies
CTR20241410
/ Not yet recruitingPhase 1
BR115注射液在晚期恶性实体肿瘤患者中的安全性、耐受性和有效性的I期临床研究
[Translation] A Phase I clinical study on the safety, tolerability and efficacy of BR115 injection in patients with advanced malignant solid tumors
100 Clinical Results associated with BR-115
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100 Translational Medicine associated with BR-115
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100 Patents (Medical) associated with BR-115
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100 Deals associated with BR-115
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Advanced Malignant Solid NeoplasmPhase 1
China
BioRay Biopharmaceutical Co., Ltd.BioRay Biopharmaceutical Co., Ltd.
01 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
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Approval

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Biosimilar

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Competitive landscape of biosimilars in different countries/locations. Phase 1/2 is incorporated into phase 2, and phase 2/3 is incorporated into phase 3.

Regulation

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