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Last update 20 Mar 2025
DS-1055
Last update 20 Mar 2025
Overview
Basic Info
Drug Type Monoclonal antibody |
Synonyms |
Target |
Action modulators |
Mechanism LRRC32 modulators(Transforming growth factor beta activator LRRC32 modulators) |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
Drug Highest PhasePhase 1 |
First Approval Date- |
Regulation- |
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Related
1
Clinical Trials associated with DS-1055NCT04419532
A Phase 1, First In Human Study of DS-1055a in Subjects With Relapsed or Refractory Locally Advanced or Metastatic Solid Tumors
100 Clinical Results associated with DS-1055
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100 Translational Medicine associated with DS-1055
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100 Patents (Medical) associated with DS-1055
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1
Literatures (Medical) associated with DS-105523 Jul 2021International ImmunologyQ3 · MEDICINE
Novel anti-GARP antibody DS-1055a augments anti-tumor immunity by depleting highly suppressive GARP+ regulatory T cells
Q3 · MEDICINE
Article
Author: Tuettenberg, Andrea ; Sugiyama, Daisuke ; Hata, Masato ; Hayashi, Shinko ; Satoh, Kazuki ; Nishikawa, Hiroyoshi ; Hirahara, Kazuki ; Agatsuma, Toshinori ; Ishida, Saori ; Sato, Takahiko ; Jonuleit, Helmut ; Kozuma, Shiho ; Wakita, Kenichi ; Fujimaki, Kaori ; Maruyama, Shoichi ; Amano, Masato ; Okamoto, Atsushi ; Wada, Teiji ; Watanabe, Ichiro ; Lim, Kyungtaek ; Kobayashi, Yoichi ; Tanemura, Atsushi ; Miyamoto, Megumi ; Kadokura, Michinori
100 Deals associated with DS-1055
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R&D Status
10 top R&D records. to view more data
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Advanced cancer | Phase 1 | United States | 09 Oct 2020 | |
| Advanced cancer | Phase 1 | Japan | 09 Oct 2020 | |
| Advanced cancer | Phase 1 | Canada | 09 Oct 2020 | |
| Esophageal Carcinoma | Phase 1 | Japan | 09 Oct 2020 | |
| Melanoma | Phase 1 | Japan | 09 Oct 2020 | |
| Metastatic Solid Tumor | Phase 1 | Canada | 09 Oct 2020 | |
| Metastatic Solid Tumor | Phase 1 | United States | 09 Oct 2020 | |
| Metastatic Solid Tumor | Phase 1 | Japan | 09 Oct 2020 | |
| Non-Small Cell Lung Cancer | Phase 1 | Japan | 09 Oct 2020 | |
| Stomach Cancer | Phase 1 | Japan | 09 Oct 2020 |
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