Last update 16 Aug 2025

SYH-2043

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
CPO-166, CPO166, SYH 2043
+ [1]
Target
CDK2 x CDK4 x CDK6
Action
inhibitors
Mechanism
CDK2 inhibitors(Cyclin-dependent kinase 2 inhibitors), CDK4 inhibitors(Cyclin-dependent kinase 4 inhibitors), CDK6 inhibitors(Cyclin-dependent kinase 6 inhibitors)
Therapeutic Areas
NeoplasmsSkin and Musculoskeletal Diseases
Active Indication
Breast CancerAdvanced cancerMetastatic breast cancer+ [1]
Inactive Indication-
Originator Organization
CSPC Ouyi Pharmaceutical Co., Ltd.CSPC Ouyi Pharmaceutical Co., Ltd.
Active Organization
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.CSPC Ouyi Pharmaceutical Co., Ltd.CSPC Ouyi Pharmaceutical Co., Ltd.CSPC Pharmaceutical Group Ltd.CSPC Pharmaceutical Group Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePhase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with SYH-2043
NCT05728541
/ Not yet recruitingPhase 1
A Phase I Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetic Profile and Preliminary Efficacy of SYH2043 in Patients With Advanced Malignant Tumors
100 Clinical Results associated with SYH-2043
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100 Translational Medicine associated with SYH-2043
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100 Patents (Medical) associated with SYH-2043
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100 Deals associated with SYH-2043
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Breast CancerPhase 1
China
CSPC Pharmaceutical Group Ltd.CSPC Pharmaceutical Group Ltd.
14 Jun 2023
Advanced cancerPhase 1
China
CSPC Ouyi Pharmaceutical Co., Ltd.CSPC Ouyi Pharmaceutical Co., Ltd.
23 Mar 2023
Metastatic breast cancerPhase 1
China
Conjupro Biotherapeutics, Inc.Conjupro Biotherapeutics, Inc.
-
Advanced breast cancerIND Approval
China
CSPC Ouyi Pharmaceutical Co., Ltd.CSPC Ouyi Pharmaceutical Co., Ltd.
10 Apr 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
Phase
PopulationAnalyzed EnrollmentGroupResultsEvaluationPublication Date

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Clinical Trial

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Approval

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Regulation

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