Last update 30 Mar 2025

SR-8541A

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
ENPP1 inhibitor (Translational Genomics Research Institute), STING agonist (Translational Genomics Research Institute), SR 8541A
+ [1]
Target
ENPP1
Action
inhibitors
Mechanism
ENPP1 inhibitors(Ectonucleotide pyrophosphatase/phosphodiesterase family member 1 inhibitors)
Therapeutic Areas
NeoplasmsDigestive System Disorders
Active Indication
Metastatic Microsatellite Stable Colorectal CarcinomaAdvanced Malignant Solid NeoplasmNeoplasms
Inactive Indication-
Originator Organization
Translational Genomics Research InstituteTranslational Genomics Research Institute
Active Organization
Stingray Therapeutics, Inc.Stingray Therapeutics, Inc.StartupTranslational Genomics Research InstituteTranslational Genomics Research Institute
Inactive Organization-
Drug Highest PhasePhase 2
First Approval Date-
Regulation-
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Related

2
Clinical Trials associated with SR-8541A
NCT06589440
/ RecruitingPhase 2
Phase 2 Study of SR-8541A in Combination with Botensilimab and Balstilimab in Subjects with Refractory Metastatic Microsatellite Stable Colorectal Cancer (MSS-CRC)
NCT06063681
/ RecruitingPhase 1
Phase 1, Dose Escalation, Safety, Tolerability, and Pharmacokinetic Study of SR-8541A (ENPP1 Inhibitor) Administered Orally As Monotherapy or in Combination with Checkpoint Inhibitors in Subjects with Advanced/Metastatic Solid Tumors
100 Clinical Results associated with SR-8541A
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100 Translational Medicine associated with SR-8541A
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100 Patents (Medical) associated with SR-8541A
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100 Deals associated with SR-8541A
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Metastatic Microsatellite Stable Colorectal CarcinomaPhase 2
United States
Stingray Therapeutics, Inc.Stingray Therapeutics, Inc.Startup
20 Nov 2024
Advanced Malignant Solid NeoplasmPhase 1
Australia
Stingray Therapeutics, Inc.Stingray Therapeutics, Inc.Startup
12 Oct 2023
NeoplasmsPreclinical
United States
Translational Genomics Research InstituteTranslational Genomics Research Institute
-
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Clinical Result

Indication
Phase
Evaluation
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Approval

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Regulation

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