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Last update 08 May 2025
NBT-018
Last update 08 May 2025
Overview
Basic Info
Drug Type Degradable Molecular Glue |
Synonyms |
Action inhibitors, modulators, degraders |
Mechanism CRBN inhibitors(Cereblon inhibitors), IKZF1 modulators(DNA-binding protein Ikaros modulators), IKZF2 degraders(Zinc finger protein helios degraders) + [1] |
Therapeutic Areas |
Active Indication |
Inactive Indication- |
Originator Organization |
Active Organization |
Inactive Organization- |
License Organization- |
Drug Highest PhasePreclinical |
First Approval Date- |
Regulation- |
R&D Status
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| Indication | Highest Phase | Country/Location | Organization | Date |
|---|---|---|---|---|
| Leukemia | Preclinical | United States | 06 Nov 2022 |
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Clinical Result
Clinical Result
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