Delving into the Latest Updates on Disodium Edetate Hydrate/Cetrimide with Synapse

Overview

Basic Info

Drug Type

Small molecule drug

Synonyms

MORHONINE, モルホニン

Target-

Mechanism-

Therapeutic Areas-

Active Indication-

Inactive Indication-

Originator Organization

Showa Yakuhin Kako Co., Ltd.

Active Organization

Showa Yakuhin Kako Co., Ltd.

Inactive Organization-

Drug Highest PhaseApproved

First Approval Date

JP (07 Apr 1964)

Regulation-

Login to view timeline

Structure

Molecular FormulaC17H38N

InChIKeyGLFDLEXFOHUASB-UHFFFAOYSA-N

CAS Registry10182-92-0

View All Structures (2)

AbstractThe purpose of this study was to evaluate the spreading of root canal irrigants on human root dentine. The spreading of various solutions on dentine surfaces was measured after pre‐treatment with various conditional solutions. Seven experimental groups were set based on the combination of conditioning solution‐test solution: none‐distilled water; none‐6% sodium hypochlorite (NaOCl); none‐14.3% ethylenediaminetetraacetic acid containing surfactant 0.084% cetrimide (Morhonine®); NaOCl‐NaOCl; NaOCl‐Morhonine®; Morhonine®‐Morhonine® and Morhonine®‐NaOCl. After application of 0.1 mL of conditioning solution for 60 s, 0.5 µL of test solution was placed on dentine surfaces. Spreading of test solution was measured for 480 s to examine the size of the contact area ratio. Those at 300 s were compared among groups using Fisher’s Protected Least Significant Difference (P < 0.05). It was concluded that the contact area ratio of Morhonine®‐NaOCl increased the most significantly among all the experimental groups.

100 Deals associated with Disodium Edetate Hydrate/Cetrimide

Login to view more data