Last update 08 May 2025

p53 stimulants/PPP5C inhibitors(Shanghai Hengrui)

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
Target
PPP5C x p53
Action
inhibitors, stimulants
Mechanism
PPP5C inhibitors(protein phosphatase 5 catalytic subunit inhibitors), p53 stimulants(Tumor protein p53 stimulants)
Therapeutic Areas
NeoplasmsNervous System DiseasesOther Diseases
Active Indication
Glioblastoma
Inactive Indication-
Originator Organization
Shanghai Hengrui Pharmaceutical Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.
Active Organization
Shanghai Hengrui Pharmaceutical Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.
Inactive Organization-
License Organization-
Drug Highest PhasePreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC16H15NO4
InChIKeyKZVHQCVKMCBKRP-RQJABVFESA-N
CAS Registry-

Related

100 Clinical Results associated with p53 stimulants/PPP5C inhibitors(Shanghai Hengrui)
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100 Translational Medicine associated with p53 stimulants/PPP5C inhibitors(Shanghai Hengrui)
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100 Patents (Medical) associated with p53 stimulants/PPP5C inhibitors(Shanghai Hengrui)
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1
Literatures (Medical) associated with p53 stimulants/PPP5C inhibitors(Shanghai Hengrui)
12 Sep 2024Journal of Medicinal Chemistry
Design and Synthesis of 7-Oxabicyclo[2.2.1]heptane-2,3-dicarboxylic Acid Derivatives as PP5 Inhibitors To Reverse Temozolomide Resistance in Glioblastoma Multiforme
100 Deals associated with p53 stimulants/PPP5C inhibitors(Shanghai Hengrui)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
GlioblastomaPreclinical
China
Shanghai Hengrui Pharmaceutical Co., Ltd.Shanghai Hengrui Pharmaceutical Co., Ltd.
13 Aug 2024
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Clinical Result

Indication
Phase
Evaluation
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Study
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Deal

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Clinical Trial

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Approval

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Regulation

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