Last update 11 Jul 2026

NB-533

Overview

Basic Info

Drug Type
Small molecule drug
Synonyms
NB 533, NB533
Target
BACE1
Action
inhibitors
Mechanism
BACE1 inhibitors(Beta-secretase 1 inhibitors)
Therapeutic Areas
Nervous System Diseases
Active Indication-
Inactive Indication
Alzheimer Disease
Originator Organization
Novartis AGNovartis AG
Active Organization-
Inactive Organization
Novartis AGNovartis AG
License Organization-
Drug Highest PhasePendingPreclinical
First Approval Date-
Regulation-

Structure/Sequence

Molecular FormulaC33H55N3O4
InChIKeyMNENNUUKHSBOKZ-BEOVBFIISA-N
CAS Registry1146544-18-4

Related

100 Clinical Results associated with NB-533
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100 Translational Medicine associated with NB-533
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100 Patents (Medical) associated with NB-533
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1
Literatures (Medical) associated with NB-533
01 Mar 2009Bioorganic & medicinal chemistry lettersQ4 · MEDICINE
Macrocyclic peptidomimetic β-secretase (BACE-1) inhibitors with activity in vivo
Q4 · MEDICINE
100 Deals associated with NB-533
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R&D Status

10 top R&D records.
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IndicationHighest PhaseCountry/LocationOrganizationDate
Alzheimer DiseasePreclinical
Switzerland
Novartis AGNovartis AG
01 Mar 2009
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Clinical Result

Indication
Phase
Evaluation
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Clinical Trial

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Approval

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Regulation

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