Last update 18 Mar 2026

CD123+CLL-1 CAR-T(Hematology Hospital of Chinese Academy of Medical Sciences)

Overview

Basic Info

Drug Type
CAR-T
Synonyms
JY-017
Target
CD123 x CLL-1
Action
modulators
Mechanism
CD123 modulators(Interleukin-3 receptor subunit alpha modulators), CLL-1 modulators(C-Type lectin domain family 12 member A modulators)
Therapeutic Areas
NeoplasmsHemic and Lymphatic Diseases
Active Indication
Refractory acute myeloid leukemiaRelapsing acute myeloid leukemia
Inactive Indication-
Originator Organization
Hematology Hospital of Chinese Academy of Medical Sciences
Active Organization
Hematology Hospital of Chinese Academy of Medical Sciences
Inactive Organization-
License Organization-
Drug Highest PhaseEarly Phase 1
First Approval Date-
Regulation-
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Related

1
Clinical Trials associated with CD123+CLL-1 CAR-T(Hematology Hospital of Chinese Academy of Medical Sciences)
NCT07201727
/ Not yet recruitingEarly Phase 1IIT
Early Clinical Study of CD123+CLL-1 Dual-target CAR-T Cells Sequential Infusion CD7 CAR-T Cells and Bridging to Allogeneic Hematopoietic Stem Cell Transplantation for the Treatment of Relapsed and Refractory Acute Myeloid Leukemia
100 Clinical Results associated with CD123+CLL-1 CAR-T(Hematology Hospital of Chinese Academy of Medical Sciences)
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100 Translational Medicine associated with CD123+CLL-1 CAR-T(Hematology Hospital of Chinese Academy of Medical Sciences)
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100 Patents (Medical) associated with CD123+CLL-1 CAR-T(Hematology Hospital of Chinese Academy of Medical Sciences)
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100 Deals associated with CD123+CLL-1 CAR-T(Hematology Hospital of Chinese Academy of Medical Sciences)
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R&D Status

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IndicationHighest PhaseCountry/LocationOrganizationDate
Refractory acute myeloid leukemiaPhase 1-
Hematology Hospital of Chinese Academy of Medical Sciences
30 Sep 2025
Relapsing acute myeloid leukemiaPhase 1-
Hematology Hospital of Chinese Academy of Medical Sciences
30 Sep 2025
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Clinical Result

Indication
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Clinical Trial

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Approval

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Regulation

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